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Displaying results 2241 - 2250 of 10000 in total
  1. Drug

    (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione

    go.drugbank.com/drugs/DB08761
    Experimental

    Synonyms: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione
  2. Drug

    5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione

    go.drugbank.com/drugs/DB03368
    Experimental

    Synonyms: 5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione
  3. Drug

    Methyl vanillate

    go.drugbank.com/drugs/DB08711
    Experimental

    Synonyms: 4-hydroxy-3-methoxy methyl benzoate, Methyl 3-methoxy-4-hydroxybenzoate
  4. Drug

    Venadaparib

    go.drugbank.com/drugs/DB17105
    Investigational

    Synonyms: 1(2h)-phthalazinone, 4-((3-((3-((cyclopropylamino)methyl)-1-azetidinyl)carbonyl)-4-fluorophenyl)methyl)-, 4-((3-((3-((cyclopropylamino)methyl)-1-azetidinyl)carbonyl)-4-fluorophenyl)methyl)-1(2h)-phthalazinone
  5. Drug

    4-S-Glutathionyl-5-pentyl-tetrahydro-furan-2-ol

    go.drugbank.com/drugs/DB04521
    Experimental

    Synonyms: 4-S-Glutathionyl-5-pentyl-tetrahydro-furan-2-ol
  6. Drug

    Simvastatin

    go.drugbank.com/drugs/DB00641
    ApprovedInvestigational

    More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid and is … were found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while simvastatin has been found to have an average decrease in LDL-C of ~35%.

    Mixtures: ZINTREPID® 10 MG/40 MG, ZETIROL S ® 10 MG/40 MG TABLETASCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  7. Drug

    Cabazitaxel

    go.drugbank.com/drugs/DB06772
    ApprovedInvestigational

    Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. … [A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSynonyms: 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA.-TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE)
  8. Drug

    Icalcaprant

    go.drugbank.com/drugs/DB21651
    Investigational

    Icalcaprant is a small molecule drug. The usage of the INN stem '-caprant' in the name indicates that Icalcaprant is a kappa-opioid receptor (KOR) antagonist. … Icalcaprant is under investigation in clinical trial NCT06696755 (A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

    Synonyms: 4-(4-{[(2S)-2-(3-methoxy-1-methyl-1H-pyrazol-4-yl)pyrrolidin-1-yl]methyl}phenoxy)benzamide
  9. Drug

    EP-0042

    go.drugbank.com/drugs/DB18120
    Investigational

    Salts: EP-0042 fumarateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    SYD-003

    go.drugbank.com/drugs/DB17106
    Experimental

    Synonyms: (5-amino-1-(4-fluoro-phenyl)-1h-pyrazol-4-yl)-(3-(2,3-dihydroxy-propoxy)-phenyl)-methanone, [5-Amino-1-(4-fluoro-phenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxy-propoxy)-phenyl]-methanoneCategories: Heterocyclic Compounds, 1-Ring