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Displaying results 2281 - 2290 of 5506 in total
  1. Drug

    OPC-28326

    go.drugbank.com/drugs/DB05461
    Experimental

    It is the only clinical compound with this profile. It is currently being investigated in the treatment of peripheral vascular diseases and Raynaud's syndrome. … At low doses, OPC 28326 selectively vasodilates the femoral arterial bed due to its inhibitory action at alpha-2-adrenoceptors while having minimal action on systemic blood pressure, heart rate and coronary

  2. Drug

    Cladosporium herbarum

    go.drugbank.com/drugs/DB10865
    Approved

    Cladosporium herbarum is a fungus which can provoke allergic reactions. Cladosporium herbarum extract is used in allergenic testing.

    Mixtures: Treatment Set TS332229, Treatment Set TS332091
  3. Drug

    Salix nigra pollen

    go.drugbank.com/drugs/DB10398
    Approved

    Salix nigra pollen is the pollen of the Salix nigra plant. Salix nigra pollen is mainly used in allergenic testing.

    Mixtures: Treatment Set TS333938, Treatment Set TS128872
  4. Drug

    Eteplirsen

    go.drugbank.com/drugs/DB06014
    ApprovedInvestigational

    It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA. … [A244930] It is caused by loss-of-function mutations in the DMD gene coding for dystrophin, an essential protein involved in maintaining the structural integrity and function of muscle fibres.

  5. Drug

    Difelikefalin

    go.drugbank.com/drugs/DB11938
    ApprovedInvestigational

    [A237610] Further investigations revealed that dynorphins, endogenous agonists of KORs, work to inhibit the itching sensation at the spinal cord level, and scratching could be elicited in mouse models

  6. Drug

    Lutetium Lu-177 vipivotide tetraxetan

    go.drugbank.com/drugs/DB16778
    ApprovedInvestigational

    It consists of a radionuclide, [lutetium Lu-177], linked to a moiety that binds to PSMA, a transmembrane protein that is expressed in prostate cancer.

  7. Drug

    Pexidartinib

    go.drugbank.com/drugs/DB12978
    ApprovedInvestigational

    [A182243] Pexidartinib is available in oral formulations and it is commonly marketed as Turalio.[L7901] … Pexidartinib was originally developed by Daiichi Sankyo, Inc. and it was approved by the FDA in August 2019 as the first systemic therapy for adult patients with symptomatic tenosynovial giant cell tumor

  8. Drug

    Lazertinib

    go.drugbank.com/drugs/DB16216
    ApprovedInvestigational

    [A264289] It was approved by the FDA on August 19, 2024.[L51189] Lazertinib is used alone or in combination with other chemotherapeutic agents.[L51184]

  9. Drug

    Velusetrag

    go.drugbank.com/drugs/DB12702
    Investigational

    It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance.

  10. Drug

    Perboric acid

    go.drugbank.com/drugs/DB13235
    Approved

    [A33037] It is one of the peroxy acid salts with very wide functionalities in industrial settings. … Perboric acid is mainly found in its salt form of sodium perborate and it can be found as a monohydrate or tetrahydrate.