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Nemolizumab
go.drugbank.com/drugs/DB15252ApprovedInvestigational[A264274] It was later approved by the FDA on August 13, 2024, for the treatment of prurigo nodularis.[L51169]
Ponesimod
go.drugbank.com/drugs/DB12016ApprovedInvestigational[A232079] Fingolimod's activity at sphingosine 1-phosphate receptor 3 was suspected to be responsible for a portion of it's adverse effects, and so more selective modulators were developed.
Lotilaner
go.drugbank.com/drugs/DB17992ApprovedInvestigationalVet approved[A260741] On July 25, 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and only approved therapeutic for this condition.[L47551]
Enoxolone
go.drugbank.com/drugs/DB13089InvestigationalEnoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid Excess (AME).
Mixtures: ANZİBEL 5 MG/4 MG/3 MG EKİNEZYALI PASTİL, 20 ADET, ANZİBEL 5 MG/4 MG/3 MG MEYANBALLI PASTİL, 20 ADETHyperforin
go.drugbank.com/drugs/DB01892InvestigationalNutraceuticalOne of the most important members of this family, due to its medical properties, is _Hypericum perforatum_, also known as St John's wort.
rsPSMA Vaccine
go.drugbank.com/drugs/DB06361ApprovedWithdrawnprostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA (Schulke et
Abarelix
go.drugbank.com/drugs/DB00106ApprovedWithdrawnIt is marketed by Praecis Pharmaceuticals as Plenaxis. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market.
Safrazine
go.drugbank.com/drugs/DB09253ApprovedWithdrawnIn 1960, it was used as an antidepressant but it is now discontinued.
Cochliobolus spicifer
go.drugbank.com/drugs/DB10818ApprovedCochliobolus spicifer is a fungus which can provoke allergic reactions. Cochliobolus spicifer extract is used in allergenic testing.
Mixtures: Treatment Set TS128871Asparaginase Erwinia chrysanthemi
go.drugbank.com/drugs/DB08886ApprovedInvestigationalIt works by depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and cell survival of malignant cells, leading to cell death. … A236359] Asparaginase _Erwinia chrysanthemi_ was first approved by the FDA in November 2011 to treat patients with acute lymphoblastic leukemia (ALL) who are allergic to _E. coli_-derived asparaginase: it