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Displaying results 241 - 250 of 10000 in total
  1. Drug

    2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide

    go.drugbank.com/drugs/DB03509
    Experimental

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide
  2. Drug

    N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE

    go.drugbank.com/drugs/DB07334
    Experimental

    Synonyms: N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE
  3. Drug

    2',3'-Dideoxythymidine-5'-Monophosphate

    go.drugbank.com/drugs/DB03150
    Experimental

    Synonyms: 2',3'-Dideoxythymidine-5'-Monophosphate
  4. Drug

    Uridylyl-2'-5'-phospho-adenosine

    go.drugbank.com/drugs/DB03447
    Experimental

    Synonyms: Uridylyl-2'-5'-phospho-adenosine
  5. Drug

    Cytidyl-2'-5'-phospho-guanosine

    go.drugbank.com/drugs/DB03638
    Experimental

    Synonyms: Cytidyl-2'-5'-phospho-guanosine
  6. Drug

    5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID

    go.drugbank.com/drugs/DB07684
    Experimental

    Synonyms: 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID
  7. Drug

    Histamine

    go.drugbank.com/drugs/DB05381
    ApprovedInvestigational

    It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. … A depressor amine derived by enzymatic decarboxylation of histidine.

    Mixtures: Histamine DHCl 0.10 Percent and Menthol 2 Percent, DR. MIKES Ponos Pain Relief Cream Roll-OnCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A Inhibitors
  8. Drug

    Streptomycin

    go.drugbank.com/drugs/DB01082
    ApprovedInvestigationalVet approved

    [A233325,A232294] Although streptomycin was the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of favor due to resistance and is now primarily used as … Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s.

    Synonyms: 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranosideCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  9. Drug

    Oteseconazole

    go.drugbank.com/drugs/DB13055
    ApprovedInvestigational

    [A247035] In contrast with oteseconazole, other antifungals with imidazole or triazole moieties, such as [ketoconazole] or [fluconazole], have a high number of drug-drug interactions due to their interaction … [L41635] CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes.

    Synonyms: (R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol, 2-Pyridineethanol, α-(2,4difluorophenyl)-β β-difluoro- α-(1H-tetrazol-1-ylmethyl)-5-(4-(2,2,2-trifluoroethoxy)phenyl)-,(αR)Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Defactinib

    go.drugbank.com/drugs/DB12282
    ApprovedInvestigational

    Defactinib is a small molecule kinase inhibitor targeted against focal adhesion kinase (FAK) and proline-rich tyrosine kinase-2 (Pyk2), the two members of the FAK family of nonreceptor tyrosine kinases … [L53198,L53208] FAK is important for the integrin-mediated activation of several downstream signal transduction pathways, including those involving RAS/MEK/ERK and PI3K/Akt, and its upregulation is a key

    Synonyms: N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamideCategories: MATE 2 Inhibitors, Cytochrome P-450 Substrates