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Cyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approved[A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: CYLORİN 100 MG YUMUŞAK KAPSÜL, 50 ADET, LYMUNİR 100 MG YUMUŞAK KAPSÜL, 50 ADETFepixnebart
go.drugbank.com/drugs/DB19079InvestigationalFepixnebart is under investigation in clinical trial NCT04456686 (Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis).
Synonyms: Ly3016859 (humanized monoclonal antibody to human tgf.alpha. and epiregulin)Ketamine
go.drugbank.com/drugs/DB01221ApprovedInvestigationalVet approvedIt started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic effects. … It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.[L1332]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 2-(o-chlorophenyl)-2-(methylamino)-cyclohexanoneEpirubicin
go.drugbank.com/drugs/DB00445ApprovedInvestigationalThe compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Synonyms: (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-ARABINO-HEXOPYRANOSIDE, 5,12-NAPHTHACENEDIONE, 10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-ARABINO-HEXOPYRANOSYL)OXY)-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-, (8S-CIS)-Products: PIRUCIN 10 MG/5 ML IV INTRAVESIKAL ENJEKSİYON ICIN LIYOFİLİZE TOZ ICEREN FLAKON, 1 ADET, PHARMORUBICIN CS INJECTION 10 mg/5 mlRocuronium
go.drugbank.com/drugs/DB00728ApprovedInvestigationalIt is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery … [Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium.
Products: ANTARİN 100 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADET, MUSCOBLOC 100 MG/10 ML İ.V. ENJEKSİYONLUK ÇÖZELTİ, 10 ADETInfliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalBy binding to both the soluble subunit and the membrane-bound precursor of TNF-α [A106], infliximab disrupts the interaction of TNF-α with its receptors and may also cause lysis of cells that produce TNF-α … There are currently two biosilimars of infliximab available in the US market that demonstrate a high degree of similarity to the reference product, Remicade.
Synonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMERProducts: REMSIMA 100 MG, INFLECTRA 100 MGFlurbiprofen
go.drugbank.com/drugs/DB00712ApprovedInvestigationalFlurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis. … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen.
Mixtures: FULDUO 100 MG/8 MG FİLM KAPLI TABLET, 14 ADET, KLORHEX PLUS 2.5 MG/ML + 1.2 MG/ML GARGARA,200 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesMeperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. … Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: PETHIDINE ANTIJEN INJ. 100 MG 10 AMPUL, ALDOLAN 100 MG/2 ML AMPUL, 5 ADETFerric cation
go.drugbank.com/drugs/DB13949ApprovedWithdrawnBy mass, it is the most common element on Earth. … Resulting from inadequate supply of iron to cells due to depletion of stores, iron deficiency is the most common nutritional deficiency worldwide, particularly affecting children, women of childbearing
Mixtures: MALTOFER FOL 100 MG/0.35 MG TABLET, 30 ADET, FERIMAX FORT ÇİĞNEME TABLETİ, 30 ADETProducts: FERIMAX 100 MG/5 ML ORAL SOLUSYON 10 FLAKON, FERRUM HAUSMANN 100 MG/5 ML ORAL ÇÖZELTİ, 20 ADETSurovatamig
go.drugbank.com/drugs/DB19420InvestigationalTNB-486 is under investigation in clinical trial NCT06564038 (A Study of AZD0486 Monotherapy or in Combination With Other Anti-cancer Agents for Mature B-cell Malignancies).
Synonyms: H-gamma4 heavy chain anti-CD3D/CD3E dimer, Homo sapiens (1-450) [VH (Homo sapiens IGHV3-9*01 (100%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123)-Homo sapiens IGHG4*01 nG4m(