Search

Displaying results 241 - 250 of 2348 in total
  1. Drug

    Netarsudil

    go.drugbank.com/drugs/DB13931
    ApprovedInvestigational

    A Rho kinase inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous As of December 18, 2017 the FDA approved Aerie Pharmaceutical's Rhopressa (netarsudil ophthalmic … Acting as both a rho kinase inhibitor and a norepinephrine transport inhibitor, Netarsudil is a novel glaucoma medication in that it specifically targets the conventional trabecular pathway of aqueous

  2. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat

    Mixtures: AMZOL FEM®, MEBINOL COMPLEXCategories: Genito Urinary System and Sex Hormones
  3. Drug

    Brivoligide

    go.drugbank.com/drugs/DB16116
    Investigational

    Brivoligide is under investigation in clinical trial NCT04104919 (Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores).

    Synonyms: D(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g) (1:1), Dna, d(c-t-a-c-g-c-c-c-a-c-c-g-c-c-c-a-c-g-c-a-t-a-c), complex with dna d(g-t-a-t-g-c-g-t-g-g-g-c-g-g-t-g-g-g-c-g-t-a-g) (1:1)
  4. Drug

    Acetylcarnitine

    go.drugbank.com/drugs/DB08842
    ApprovedInvestigational

    The main role of acetylcarnitine is to help transport fatty acids into the mitochondrial matrix where fatty acid metabolism occurs.

  5. Drug

    TERT-572

    go.drugbank.com/drugs/DB17286
    Investigational

    Synonyms: H-arg-leu-phe-phe-tyr-arg-lys-ser-val-oh
  6. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    Leucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis. Unlike folic acid, leucovorin does not require the enzyme dihydrofolate reductase (DH...

    Mixtures: FERRITIN COMPLEXCategories: Vitamin B Complex
  7. Drug

    Lumacaftor

    go.drugbank.com/drugs/DB09280
    ApprovedInvestigational

    Mutations in the CFTR gene result in altered production, misfolding, or function of the CFTR protein and consequently abnormal fluid and ion transport across cell membranes. … Consequently, lumacaftor increases successful production of CFTR ion channels and the total number of receptors available for use at the cell membrane for fluid and ion transport.

  8. Drug

    Atidarsagene autotemcel

    go.drugbank.com/drugs/DB17538
    ApprovedInvestigational

    Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using

    Categories: Autologous Hematopoietic Stem Cell-Based Gene Therapy, Complex MixturesSynonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene
  9. Drug

    Ubidecarenone

    go.drugbank.com/drugs/DB09270
    ApprovedInvestigationalNutraceutical

    Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid...

    Mixtures: Complex, ComplexCategories: Electron Transport Chain Complex Proteins
  10. Drug

    Medium-chain triglycerides

    go.drugbank.com/drugs/DB13959
    ApprovedInvestigational

    In the body, MCTs are broken down into glycerol and free fatty acids, which are directly absorbed into the blood stream and transported to the target organs to exert a range of biological and metabolic