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Displaying results 241 - 250 of 10000 in total
  1. Drug

    (9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene

    go.drugbank.com/drugs/DB01834
    Experimental

    Synonyms: (9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene
  2. Drug

    (9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene

    go.drugbank.com/drugs/DB04187
    Experimental

    Synonyms: (9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene
  3. Drug

    Didanosine

    go.drugbank.com/drugs/DB00900
    ApprovedInvestigational

    A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative

    Synonyms: 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-olCategories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Zopiclone

    go.drugbank.com/drugs/DB01198
    ApprovedInvestigational

    In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like properties. … Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesSynonyms: 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate
  5. Drug

    Chlorothymol

    go.drugbank.com/drugs/DB19375
    Approved

    Chlorotymol is a [Thymol] derivative.

    Synonyms: 4-chloro-5-methyl-2-(1-methylethyl)phenol, Phenol, 4-chloro-5-methyl-2-(1-methylethyl)-
  6. Drug

    Senlizumab

    go.drugbank.com/drugs/DB17894
    Experimental

    Synonyms: BAY-10-3356
  7. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    TCAs also block histamine-H<sub>1</sub> receptors, &alpha;<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred … See toxicity section below for a complete listing of side effects.

    Synonyms: 5-(γ-methylaminopropyl)iminodibenzyl, 5-(gamma-methylaminopropyl)iminodibenzylCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor Antagonists
  8. Drug

    Prasterone

    go.drugbank.com/drugs/DB01708
    ApprovedInvestigationalNutraceutical

    Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. … In Canada, a prescription is required to buy DHEA.

    Categories: 17-Ketosteroids, Cytochrome P-450 SubstratesSynonyms: 3β-hydroxyandrost-5-en-17-one, 3beta-hydroxyandrost-5-en-17-one
  9. Drug

    Azathioprine

    go.drugbank.com/drugs/DB00993
    ApprovedInvestigational

    [L11214] Azathiprine was granted FDA approval on 20 March 1968.[L11214] … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic

    Synonyms: 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurineCategories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  10. Drug

    Tavaborole

    go.drugbank.com/drugs/DB09041
    Approved

    Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes … Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).

    Synonyms: 5-Fluoro-2,1-benzoxaborol-1(3H)-ol, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole