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Displaying results 2551 - 2560 of 10000 in total
  1. Drug

    Zidovudine

    go.drugbank.com/drugs/DB00495
    ApprovedInvestigational

    A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.

    Mixtures: N/A, LAVUZID® NCategories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  2. Drug

    Cabozantinib

    go.drugbank.com/drugs/DB08875
    ApprovedInvestigational

    Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. … [L15128,L15133] Cabometyx has since been granted several additional approvals for endocrine cancers, including differentiated thyroid cancer and neuroendocrine tumors.[L52710]

    Categories: Receptor Protein-Tyrosine Kinases, antagonists & inhibitors, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index
  3. Drug

    Dequalinium

    go.drugbank.com/drugs/DB04209
    Approved

    Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. … [A249255] It is a quaternary ammonium compound,[L42190] as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain.

    Synonyms: 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride, Decamethylenebis(4-aminoquinaldinium chloride)Mixtures: EFISOL-C, JASIMENTH C PASTILLES
  4. Drug

    Gabexate

    go.drugbank.com/drugs/DB12831
    Investigational

    Gabexate is a synthetic serine protease inhibitor which has been used as an anticoagulant. It also known to decrease production of inflammatory cytokines. … Gabexate has been investigated for use in cancer, ischemia-reperfusion injury, and pancreatitis.[A19218,A19219,A19220]

  5. Drug

    PF-4191834

    go.drugbank.com/drugs/DB11645
    Investigational

    PF-4191834 has been investigated for the basic science of Asthma.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Fedovapagon

    go.drugbank.com/drugs/DB11734
    Investigational

    Fedovapagon has been used in trials studying the treatment of Nocturia.

  7. Drug

    Brivanib alaninate

    go.drugbank.com/drugs/DB11865
    Investigational

    Brivanib alaninate has been investigated for the treatment of Colorectal Cancer.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Butylphthalide

    go.drugbank.com/drugs/DB12749
    Investigational

    Butylphthalide has been used in trials studying the prevention of Restenosis.

    Synonyms: 3-n-butylphthalide, DL-3-n-butylphthalideCategories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household setting
  9. Drug

    Daniquidone

    go.drugbank.com/drugs/DB12804
    Investigational

    Daniquidone has been used in trials studying the treatment of Neoplasms.

    Categories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Prednimustine

    go.drugbank.com/drugs/DB12832
    Investigational

    Prednimustine has been used in trials studying the treatment of Lymphoma.