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Displaying results 2611 - 2620 of 10000 in total
  1. Drug

    Afamitresgene autoleucel

    go.drugbank.com/drugs/DB18592
    ApprovedInvestigational

    Afamitresgene autoleucel is a melanoma-associated antigen A4 (MAGE-A4)-directed genetically modified autologous T cell immunotherapy product consisting of CD4 and CD8 positive T cells transduced with a … [L51114] The transduced T cells are expanded, washed, formulated into a suspension, and cryopreserved.

    Synonyms: HUMAN MELANOMA ANTIGEN A4 (MAGE FAMILY MEMBER A4, A, AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE
  2. Drug

    FCR001

    go.drugbank.com/drugs/DB18595
    Investigational

    FCR001 is a somatic cell therapy product containing hematopoietic progenitor cells (HPC), Facilitating Cells (FC), and alpha beta T cells.

  3. Drug

    Perenostobart

    go.drugbank.com/drugs/DB18602
    Investigational

    Perenostobart is an alpha-CD39 IgG4 monoclonal antibody.

    Synonyms: immunoglobulin G4-kappa, anti-[ENTPD1(ectonucleoside triphosphate diphosphohydrolase 1, NTPDase-1, ATPDase, SPG64, CD39)], Homo sapiens monoclonal antibody, Immunoglobulin G4 [229-proline], anti-(human ectonucleoside triphosphate diphosphohydrolase 1) (human monoclonal SRF617 γ4-chain), disulfide with human monoclonal SRF617 κ-chain, dimer
  4. Drug

    Sulfobutylether-beta-cyclodextrin

    go.drugbank.com/drugs/DB18607
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Sapablursen

    go.drugbank.com/drugs/DB18608
    Investigational

    Sapablursen is a synthetic 2'-O-(2-methoxyethyl)-modified antisense oligonucleotide linked to a tri-antennary cluster of N-acetyl galactosamine (GalNAc3) sugars targeting transmembrane protease, serine … 6 messenger ribonucleic acid

  6. Drug

    PAS-004

    go.drugbank.com/drugs/DB18611
    Investigational

    PAS-004 is an allosteric MEK 1/2 inhibitor being developed by Pasithea Therapeutics. It is being investigated for the treatment of neurofibromatosis 1 and Noonan syndrome.

  7. Drug

    ST266

    go.drugbank.com/drugs/DB18614
    Investigational

    ST266 is an amniotic membrane-derived cellular cytokine solution.

  8. Drug

    VGB-R04

    go.drugbank.com/drugs/DB18615
    Investigational

    VGB-R04 is an adeno-associated viral vector delivering human FIX Padua gene.

  9. Drug

    AAV9/MFSD8

    go.drugbank.com/drugs/DB18616
    Experimental

    AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. … It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8

    Synonyms: An adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8
  10. Drug

    WU-CART-007

    go.drugbank.com/drugs/DB18617
    Investigational

    WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.

    Synonyms: an allogeneic, fratricide-resistant genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7