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Displaying results 2681 - 2690 of 10000 in total
  1. Drug

    Aminocaproic acid

    go.drugbank.com/drugs/DB00513
    ApprovedInvestigational

    An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.

    Mixtures: NAVI Black and C-Clinic, Relief and Nature Toothpast E Jasmine MintSynonyms: 6-Aminocaproic acid, 6-aminohexanoic acid
  2. Drug

    FB-101

    go.drugbank.com/drugs/DB17956
    Investigational

    FB-101 is a c-Abl inhibitor. … Developed by 1st Biotherapeutics, it is being investigated for the treatment of neurological disorders, such as Parkinson's Disease and amyotrophic lateral sclerosis (ALS).[L47102]

    Synonyms: FB 101
  3. Drug

    Cobicistat

    go.drugbank.com/drugs/DB09065
    ApprovedInvestigational

    Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered … Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile.

    Mixtures: GENVOYA FILM COATED TABLET 150 MG/150 MG/200 MG/10 MG, STRIBILD FILM COATED TABLET 150 MG/150 MG/200 MG/245 MGCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  4. Drug

    Vonoprazan

    go.drugbank.com/drugs/DB11739
    ApprovedInvestigational

    Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H<sup>+</sup>, K<sup>+</sup>-ATPase-mediated gastric acid secretion. … [A253702] In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and clarithromycin for the treatment of _H. pylori_ infection.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine
  5. Drug

    Betula pendula pollen

    go.drugbank.com/drugs/DB11004
    Approved

    Betula pendula pollen allergenic extract is used in allergenic testing.

    Synonyms: European white birch pollenMixtures: Pollens - Trees, Tree Mix 6, Pollens - Trees, Tree Mix 6
  6. Drug

    XMT-1001

    go.drugbank.com/drugs/DB06069
    Investigational

    XMT-1001 is a polymer-based prodrug of camptothecin (CPT), a well-characterized topoisomerase I inhibitor with potent anti-tumor activity. … It is a water-soluble macromolecular conjugate of camptothecin (CPT).

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    FAV-201

    go.drugbank.com/drugs/DB06130
    Experimental

    FAV-201 is a patient-specific immunotherapy for the treatment of T-cell lymphoma.

  8. Drug

    ISB 2001

    go.drugbank.com/drugs/DB18570
    Investigational

    ISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3.

  9. Drug

    WL-1002

    go.drugbank.com/drugs/DB05346
    Experimental

    WL-1002 is developed by Winston Laboratories which is a topical cream formulation of 075% zucapaicin (also known as civamide), for the treatment of pain due to osteoarthritis.

  10. Drug

    Ferrous cation

    go.drugbank.com/drugs/DB14510
    Investigational

    Synonyms: Iron(2+), Iron(2+) ionProducts: PLASTUFER 100 MG, ERYFER 100