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Displaying results 2681 - 2690 of 10000 in total
  1. Drug

    QXL138AM

    go.drugbank.com/drugs/DB18552
    Investigational

    QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.

  2. Drug

    mRNA-3745

    go.drugbank.com/drugs/DB18554
    Investigational

    mRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human glucose 6-phosphatase (G6Pase).

  3. Drug

    Ergidina

    go.drugbank.com/drugs/DB18565
    Experimental

    Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.

    Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic RGD-4C peptide (ACDCRGDCFCG)
  4. Drug

    AB-G023

    go.drugbank.com/drugs/DB18576
    Experimental

    AB-G023 is a solution stable glucagon analog

  5. Drug

    PBGM01

    go.drugbank.com/drugs/DB18581
    Investigational

    PBGM01 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, which contains human GLB1 transgene encoding the galactosidase beta 1 enzyme.

  6. Drug

    CTR-107

    go.drugbank.com/drugs/DB18583
    Experimental

    CTR-107 is a synthetic targeted growth factor. It is being investigated for the treatment of familial exudative vitreoretinopathy.

  7. Drug

    Zelpultide alfa

    go.drugbank.com/drugs/DB18587
    Investigational

    Zelpultide alfa is a recombinant human surfactant protein D.

    Synonyms: RECOMBINANT SP-D, HUMAN PULMONARY SURFACTANT-ASSOCIATED PROTEIN D (PSPD, SURFACTANT PROTEIN D, SP-D, COLLECTIN-7, SURFACTANT PROTEIN D), NON-COVALENT QUADRUPLE TRIMER, PRODUCED IN HUMAN MYELOGENOUS LEUKEMIA K562 CELLS,
  8. Drug

    2G7

    go.drugbank.com/drugs/DB18589
    Experimental

    2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.

    Synonyms: Recombinant humanized anti-transforming growth factor (TGF) beta 3 antibody
  9. Drug

    Afamitresgene autoleucel

    go.drugbank.com/drugs/DB18592
    ApprovedInvestigational

    Afamitresgene autoleucel is a melanoma-associated antigen A4 (MAGE-A4)-directed genetically modified autologous T cell immunotherapy product consisting of CD4 and CD8 positive T cells transduced with a … [L51114] The transduced T cells are expanded, washed, formulated into a suspension, and cryopreserved.

    Synonyms: HUMAN MELANOMA ANTIGEN A4 (MAGE FAMILY MEMBER A4, A, AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE
  10. Drug

    FCR001

    go.drugbank.com/drugs/DB18595
    Investigational

    FCR001 is a somatic cell therapy product containing hematopoietic progenitor cells (HPC), Facilitating Cells (FC), and alpha beta T cells.