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Displaying results 261 - 270 of 10000 in total
  1. Drug

    BW-A 58C

    go.drugbank.com/drugs/DB06740
    Experimental

    BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy … metabolite in man in vivo and also in human liver microsomes, where this is catalysed primarily by a 54 kDa CYP2C9 form of cytochrome P450, P450hB20-27.

    Synonyms: 2-(4'-t-Butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inhibitors
  2. Drug

    Methacrylyl-Coenzyme A

    go.drugbank.com/drugs/DB01675
    Experimental

    Synonyms: Methacrylyl-Coenzyme ACategories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Dephospho Coenzyme A

    go.drugbank.com/drugs/DB03170
    Experimental

    Synonyms: Dephospho Coenzyme A
  4. Drug

    Nitromethyldethia coenzyme A

    go.drugbank.com/drugs/DB04230
    Experimental

    Synonyms: Nitromethyldethia coenzyme A
  5. Drug

    Desulfo-coenzyme A

    go.drugbank.com/drugs/DB01829
    Experimental

    Synonyms: Coenzyme A, desulfo, Desulfo-coenzyme ACategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Sinapoyl coenzyme A

    go.drugbank.com/drugs/DB03179
    Experimental

    Synonyms: Sinapoyl coenzyme A
  7. Drug

    Monophosphoryl lipid A

    go.drugbank.com/drugs/DB19290
    Investigational

    Synonyms: 3-O-DESACYL-4′-MONOPHOSPHORYL LIPID A FREE ACID, AS01E COMPONENT MPL-A
  8. Drug

    Pepsin

    go.drugbank.com/drugs/DB13198
    ApprovedWithdrawn

    Stimulation of the pancreas and therefore enzymatic digestion of food is a tightly controlled and is a hormonally mediated process. … Pepsin is often used as a replacement enzyme for those with pancreatic insufficiency [L2357].

    Mixtures: Debiline H, Glutamic Acid HCl Betaine HCl W PepsinCategories: Pepsin A, antagonists & inhibitors
  9. Drug

    Nortriptyline

    go.drugbank.com/drugs/DB00540
    ApprovedInvestigational

    Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant (TCA).

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
  10. Drug

    Agalsidase alfa

    go.drugbank.com/drugs/DB15874
    ApprovedInvestigational

    Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009.

    Synonyms: alpha-galactosidase A, Recombinant alpha-galactosidase AProducts: REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML