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Vactosertib
go.drugbank.com/drugs/DB15310InvestigationalVactosertib is under investigation in clinical trial NCT03724851 (Vactosertib in Combination With Pembrolizumab in Metastatic Colorectal or Gastric Cancer).
Synonyms: 2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]anilineCategories: Heterocyclic Compounds, 1-RingRemifentanil
go.drugbank.com/drugs/DB00899ApprovedInvestigationalRemifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia. … Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic.
Categories: Heterocyclic Compounds, 1-RingProducts: ULTIVA 1 MG ENJEKTABL TOZ İÇEREN FLAKON, 5 ADET, REMIFENTANILO 1 MG/MLIodide I-131
go.drugbank.com/drugs/DB09293ApprovedInvestigationalAs a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, while the other 90% (beta radiation) causes tissue damage without contributing to any ability to see … Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy.
Salts: Sodium iodide I-131Synonyms: 131 I, 131-ITrandolapril
go.drugbank.com/drugs/DB00519ApprovedInvestigationalIt is metabolized to its biologically active diacid form, trandolaprilat, in the liver. … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).
Mixtures: VERACOMB MR 180/2 MG KAPSÜL, 28 ADET, VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-RingAlprazolam
go.drugbank.com/drugs/DB00404ApprovedIllicitInvestigational[A18125] Alprazolam was given FDA approval on October 16, 1981.[L6148] … [A18125] Alprazolam's adverse effects are generally related to the sedation it can cause.
Synonyms: 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepineMixtures: NEUPAX DUO-SFlecainide
go.drugbank.com/drugs/DB01195ApprovedInvestigationalWithdrawnFlecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. … [A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.
Categories: MATE 1 Inhibitors, MATE 1 SubstratesSynonyms: N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamideDurvalumab
go.drugbank.com/drugs/DB11714ApprovedInvestigational[A192789] Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture,[L12621] durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote … small cell lung cancer (ES-SCLC).
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: IMFINZI 500 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, IMFINZI® 50 MG/ML CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓNBicalutamide
go.drugbank.com/drugs/DB01128ApprovedInvestigationalIt is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. Bicalutamide binds to the androgen receptor.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: BICALUTAMIDE KABI 50 MG FİLM TABLET, 20 ADET, BICALUTAMIDE EGFingolimod
go.drugbank.com/drugs/DB08868ApprovedInvestigationalIt was developed by Novartis and initially approved by the FDA in 2010.[L12651] Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with the SARS-CoV-2 virus. … Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects.
Categories: Sphingosine 1-phosphate Receptor Modulator, Sphingosine 1 Phosphate Receptor ModulatorsProducts: FİGOFİN 0.5 MG KAPSÜL, 30 ADET, FINGOLIMOD EGRiluzole
go.drugbank.com/drugs/DB00740ApprovedInvestigationalA glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: RILUZOL - CT 50 MG, RILUTEK 50 MG