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Aluminum zirconium tetrachlorohydrex gly
go.drugbank.com/drugs/DB11149ApprovedWithdrawnAluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Mixtures: Ban Ultra Antiperspirant Roll-ONProducts: Degree Roll-ON Antiperspirant, Ban Clear Ap Roll-ONVolanesorsen
go.drugbank.com/drugs/DB15067Approved[L16621] This drug is not commonly prescribed as it is used as an adjunct to diet in patients at high risk for pancreatitis, who have had inadequate response to triglyceride lowering therapy. … Volanesorsen is an antisense oligonucleotide that binds to apoC-III mRNA to prevent its translation.
Fecal microbiota
go.drugbank.com/drugs/DB17743ApprovedInvestigationalFecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of _Clostridioides difficile_ infection (CDI) in patients … [A259172] REBYOTA, a live fecal microbiota suspension for rectal use, was approved by the FDA in November 2022.
Etuvetidigene Autotemcel
go.drugbank.com/drugs/DB17593ApprovedInvestigational[A274878] The WAS protein is expressed on non-erythroid hematopoietic cells and regulates the function of actin filaments in the cytoskeleton.[A274878] … [L54693] WAS is a rare X-linked disorder caused by a mutation in the gene encoding the WAS protein, leading to a compromised immune system.
Ticagrelor
go.drugbank.com/drugs/DB08816ApprovedInvestigationalTicagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y<sub>12</sub> receptor antagonism. … [A2903] Unlike [clopidogrel], ticagrelor is not a prodrug.[A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU,[L14207].
Bisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigationalIt may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity. … [A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such
Equine Botulinum Neurotoxin E Immune FAB2
go.drugbank.com/drugs/DB13897ApprovedIt is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes E in adults and pediatric patients. … Equine Botulinum Neurotoxin E Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype E.
Equine Botulinum Neurotoxin C Immune FAB2
go.drugbank.com/drugs/DB13898ApprovedIt is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes C in adults and pediatric patients. … Equine Botulinum Neurotoxin C Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype C.
Atenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981.
Products: MIN-TTetradecyl hydrogen sulfate (ester)
go.drugbank.com/drugs/DB11328ApprovedSodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids … Sodium tetradecyl sulfate has been widely used since the 1950s, and in 1978 the first successful report of injecting a 1% solution into spider angiomas in 144 patients was made.