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AB-201
go.drugbank.com/drugs/DB18629InvestigationalAB-201 is a CAR-NK cell therapy targeted against HER2.[L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Synonyms: Ex vivo expanded allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and secrete IL-15Collagenase clostridium histolyticum
go.drugbank.com/drugs/DB00048ApprovedInvestigational[L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA for the treatment of cellulite in adult women. … Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum.
Synonyms: Clostridiopeptidase ANeisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen
go.drugbank.com/drugs/DB14427ApprovedInvestigationalNeisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Synonyms: Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigenMixtures: MENVEO®, MENVEO®Octanoyl-Coenzyme A
go.drugbank.com/drugs/DB02910ExperimentalSynonyms: Octanoyl-Coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-RingSuccinyl-Coenzyme A
go.drugbank.com/drugs/DB03699ExperimentalSynonyms: Succinyl-Coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-RingCoenzyme A persulfide
go.drugbank.com/drugs/DB04036ExperimentalCoenzyme A persulfide is a possible in vivo inhibitor of mammalian short chain acyl-CoA dehydrogenase.
Synonyms: Coenzyme A persulfideCategories: Heterocyclic Compounds, 2-RingBW-A 58C
go.drugbank.com/drugs/DB06740ExperimentalBW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy … metabolite in man in vivo and also in human liver microsomes, where this is catalysed primarily by a 54 kDa CYP2C9 form of cytochrome P450, P450hB20-27.
Synonyms: 2-(4'-t-Butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsNitromethyldethia coenzyme A
go.drugbank.com/drugs/DB04230ExperimentalSynonyms: Nitromethyldethia coenzyme ADesulfo-coenzyme A
go.drugbank.com/drugs/DB01829ExperimentalSynonyms: Coenzyme A, desulfo, Desulfo-coenzyme ACategories: Heterocyclic Compounds, 2-Ring