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Afimetoran
go.drugbank.com/drugs/DB16580InvestigationalAfimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8.
Hydrocortisone phosphate
go.drugbank.com/drugs/DB14542ApprovedInvestigationalVet approvedCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersEthyl biscoumacetate
go.drugbank.com/drugs/DB08794ApprovedWithdrawnEthyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTrilostane
go.drugbank.com/drugs/DB01108ApprovedVet approvedWithdrawnTrilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994.
PTI-801
go.drugbank.com/drugs/DB05300InvestigationalIt is a combination of oxycodone with ultralow-dose naltrexone, an opioid antagonist. … PTI-801 can minimize the opioid tolerance, dependence or addiction that is often associated with repeat use of oxycodone.
Elagolix
go.drugbank.com/drugs/DB11979ApprovedInvestigationalMoreover, women who are affected by this condition can suffer for up to six to ten years and visit multiple physicians before receiving a proper diagnosis [A35868, A35869, F801].
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsPolaprezinc
go.drugbank.com/drugs/DB09221InvestigationalPolaprezinc is a chelated form of zinc and L-carnosine. It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers . It was determined that polaprezinc may be effective in p...
International brands: Promac-D2'-Deoxyuridine
go.drugbank.com/drugs/DB02256InvestigationalAn antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. … Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. [PubChem]
Angiotensin II
go.drugbank.com/drugs/DB11842ApprovedInvestigationalin the inpatient setting and affects up to one third of patients in the intensive care unit, the FDA determined that there is a need for treatment options for critically ill hypotensive patients who do
Benzyl alcohol
go.drugbank.com/drugs/DB06770ApprovedInvestigationalMixtures: ZOLBENE CREMA TOPICA (CALAMINA 5% + OXIDO DE ZINC 5% + ALCOHOL BENCILICO 1%)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates