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Displaying results 281 - 290 of 10000 in total
  1. Drug

    Oxidized coenzyme A

    go.drugbank.com/drugs/DB01846
    Experimental

    Synonyms: Oxidized coenzyme A
  2. Drug

    Pepsin

    go.drugbank.com/drugs/DB13198
    ApprovedWithdrawn

    Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products [L2358]. … Stimulation of the pancreas and therefore enzymatic digestion of food is a tightly controlled and is a hormonally mediated process.

    Synonyms: Pepsin AMixtures: Debiline H, Glutamic Acid HCl Betaine HCl W Pepsin
  3. Drug

    Nortriptyline

    go.drugbank.com/drugs/DB00540
    ApprovedInvestigational

    Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant (TCA). … [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.[L11881]

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
  4. Drug

    Agalsidase alfa

    go.drugbank.com/drugs/DB15874
    ApprovedInvestigational

    [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009. … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta].

    Synonyms: alpha-galactosidase A, Recombinant alpha-galactosidase AProducts: REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML
  5. Drug

    Glatiramer

    go.drugbank.com/drugs/DB05259
    ApprovedInvestigational

    [A248870] Along with [human interferon beta], [teriflunomide], and [dimethyl fumarate], glatiramer acetate is a first-line drug for patients with MS. … [A248880] It was approved by the FDA in 1996, and a generic version became available in 2017.

    Synonyms: (T,G)-A-L, Copolymer I (synthetic peptide)Products: Copaxone 20 mg/ml Injektionslösung in einer Fertigspritze, Copaxone 40 mg/ml Injektionslösung in einer Fertigspritze
  6. Drug

    Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen

    go.drugbank.com/drugs/DB14427
    ApprovedInvestigational

    Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.

    Synonyms: Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigenMixtures: MENVEO®, MENVEO®
  7. Drug

    BW-A 58C

    go.drugbank.com/drugs/DB06740
    Experimental

    metabolite in man in vivo and also in human liver microsomes, where this is catalysed primarily by a 54 kDa CYP2C9 form of cytochrome P450, P450hB20-27. … BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy

    Synonyms: 2-(4'-t-Butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inhibitors
  8. Drug

    Coenzyme A persulfide

    go.drugbank.com/drugs/DB04036
    Experimental

    Coenzyme A persulfide is a possible in vivo inhibitor of mammalian short chain acyl-CoA dehydrogenase.

    Synonyms: Coenzyme A persulfideCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Octanoyl-Coenzyme A

    go.drugbank.com/drugs/DB02910
    Experimental

    Synonyms: Octanoyl-Coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring
  10. Drug

    Succinyl-Coenzyme A

    go.drugbank.com/drugs/DB03699
    Experimental

    Synonyms: Succinyl-Coenzyme ACategories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-Ring