Search

Displaying results 2901 - 2910 of 10000 in total
  1. Drug

    Tavokinogene telseplasmid

    go.drugbank.com/drugs/DB17301
    Investigational

    Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.

    Synonyms: Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus
  2. Drug

    SNS01-T

    go.drugbank.com/drugs/DB17302
    Investigational

    SNS01-T is a gene therapy nanoparticle. … It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets the native eIF5A that promotes growth/anti-apoptosis of cancer cells; and polyethylenimine.

  3. Drug

    Laurocapram

    go.drugbank.com/drugs/DB17308
    Approved

    Synonyms: 1-n-dodecylazacycloheptan-2-one, 1-dodecylazacycloheptan-2-oneCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    ENB-003

    go.drugbank.com/drugs/DB17340
    Investigational

    ENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for cancer.

  5. Drug

    MORAb-066

    go.drugbank.com/drugs/DB17347
    Investigational

    MORAb-066 is a humanized antibody directed against tissue factor (TF). It is being investigated in pancreatic cancer.

  6. Drug

    AMG 424

    go.drugbank.com/drugs/DB17357
    Investigational

    AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.

    Synonyms: Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38
  7. Drug

    MB-102 CD123 CAR

    go.drugbank.com/drugs/DB17366
    Investigational

    MB-102 are autologous T cells genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and a truncated human epidermal growth factor receptor.

  8. Drug

    Gavocabtagene autoleucel

    go.drugbank.com/drugs/DB17367
    Investigational

    Gavocabtagene autoleucel is a novel cell therapy consisting of autologous genetically engineered T cells expressing a single-domain antibody that recognizes human Mesothelin, fused to the CD3-epsilon subunit … which, upon expression, is incorporated into the endogenous T cell receptor (TCR) complex.

  9. Drug

    DCLL-9718S

    go.drugbank.com/drugs/DB17392
    Investigational

    DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). … DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine

    Synonyms: THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer
  10. Drug

    KAHR-102

    go.drugbank.com/drugs/DB17427
    Investigational

    KAHR-102 is a dual signaling protein fusing cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) to the Fas-ligand (FasL).