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Casirivimab
go.drugbank.com/drugs/DB15941ApprovedInvestigational[L23524] In November 2021, the same indication was approved by the EMA. … Casirivimab is a monoclonal antibody combined with [Imdevimab] in Regeneron's antibody cocktail known as REGN-COV2 for the treatment of COVID-19.
AMG-208
go.drugbank.com/drugs/DB08079InvestigationalAMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.
AG-858
go.drugbank.com/drugs/DB05502InvestigationalAG-858 (autologous heat-shock protein 70 peptide vaccine) is a recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes.
AMG-119
go.drugbank.com/drugs/DB17363InvestigationalAMG-119 are CAR-T cells targeting delta-like ligand 3 (DLL3).[A254811]
Apararenone
go.drugbank.com/drugs/DB15024InvestigationalApararenone is under investigation in clinical trial NCT02531568 (Drug Interaction Study of Warfarin and MT-3995).
Camsirubicin
go.drugbank.com/drugs/DB13103InvestigationalGPX-150 has been used in trials studying the treatment of Soft Tissue Sarcoma and Advanced Solid Tumors - Phase 1 Population.
Synonyms: 5(8H)-Naphthacenone, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,9,10,12-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyethyl)-12-imino-1-methoxy-, (8R,10S)-, 5-imino-13-deoxydoxorubicinPoliovirus type 1 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10795ApprovedInvestigationalPoliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis
Mixtures: HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 10 ADET, HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 10 ADETNerandomilast
go.drugbank.com/drugs/DB18237ApprovedInvestigational[L54858] In the Phase 3 FIBRONEER-ILD trial, nerandomilast led to a smaller decline in forced vital capacity (FVC) than placebo over 52 weeks. [A274591] … It has one chiral center and is the R-stereoisomer.[L54126] On October 7, 2025, nerandomilast was approved as the first new treatment for idiopathic pulmonary fibrosis in more than a decade.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEbola Zaire vaccine (live, attenuated)
go.drugbank.com/drugs/DB15595ApprovedInvestigationalThe mortality rate of the Zaire species is about 80%. … These may be accompanied by hypotension and respiratory, kidney and liver failure, as well as internal and external bleeding.
Synonyms: Ebola Zaire Vaccine (rVSV∆G-ZEBOV-GP, live), EBOLA ZAÏRE VACCINE (rVSV [DELTA] G-ZEBOV-GP, LIVE)Vayarin
go.drugbank.com/drugs/DB09328ApprovedApproximately 60% of the users who completed 12 weeks of therapy reported subjective benefits from treatment. … This drug has also been used for management of hypertriglyceridemia [L1503].
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme Inhibitors