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Displaying results 2981 - 2990 of 10000 in total
  1. Drug

    Lodoxamide

    go.drugbank.com/drugs/DB06794
    Approved

    Mast-cell stabilizers, first one approved being cromolyn sodium, are used in treatment of ocular hypersensitivity reactions such as vernal conjunctivitis. … Although less effective than topical steroids at decreasing inflammation, mast-cell stabilizers offer another treatment option and exhibit minimal adverse effects.

    Synonyms: N,N'-(2-chloro-5-cyano-m-phenylene)dioxamate
  2. Drug

    OPC-28326

    go.drugbank.com/drugs/DB05461
    Experimental

    It is the only clinical compound with this profile. It is currently being investigated in the treatment of peripheral vascular diseases and Raynaud's syndrome. … At low doses, OPC 28326 selectively vasodilates the femoral arterial bed due to its inhibitory action at alpha-2-adrenoceptors while having minimal action on systemic blood pressure, heart rate and coronary

  3. Drug

    Influenza B virus B/Phuket/3073/2013 recombinant hemagglutinin antigen

    go.drugbank.com/drugs/DB10779
    ApprovedInvestigational

    This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. … re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it

    Mixtures: Fluarix Tetra Injektionssuspension in einer Fertigspritze
  4. Drug

    Difamilast

    go.drugbank.com/drugs/DB14987
    ApprovedInvestigational

    The drug is indicated for the topical treatment of mild to moderate atopic dermatitis in adults and pediatric patients 2 years of age and older [L55042]. It is approved in Japan and the United States. … [L55042, A275424, A275420] As difamilast's mechanism of action involves the inhibition of PDE4, the inhibition leads to an increase in intracellular cyclic AMP and a subsequent decrease in the production

  5. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.

    Products: VELETRI® 1.5 MG, VELETRI®0.5 MG
  6. Drug

    Bos taurus hair

    go.drugbank.com/drugs/DB10856
    Approved

    Bos taurus hair is used in allergenic testing.

    Mixtures: Treatment Set TS333743, Treatment Set TS330316
  7. Drug

    Populus nigra pollen

    go.drugbank.com/drugs/DB10750
    Approved

    Populus nigra pollen is mainly used in allergenic testing.

    Mixtures: Treatment Set TS343826, Treatment Set TS346962
  8. Drug

    Crisaborole

    go.drugbank.com/drugs/DB05219
    ApprovedInvestigational

    It reduces the local inflammation in the skin and prevents further exacerbation of the disease with a good safety profile. … It is currently under development as topical treatment of psoriasis.

  9. Drug

    Fecal microbiota

    go.drugbank.com/drugs/DB17743
    ApprovedInvestigational

    Human fecal matter is then tested for a panel of transmissible pathogens and processed with methods aimed at preserving bacterial viability. … Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of _Clostridioides difficile_ infection (CDI) in patients

  10. Drug

    N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine

    go.drugbank.com/drugs/DB13948
    Experimental

    It has been tested with regard to the head-twitch-response (HTR) model of 5-HT2A activity and effects on locomotion [L1148]. It was discovered in 2014 at the University of Copenhagen. … 25CN-NBOH (N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine) is a newly developed selective 5-HT2A agonist.

    Synonyms: NBOH-2C-CN, N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine