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Melatonin
go.drugbank.com/drugs/DB01065ApprovedInvestigationalNutraceuticalVet approvedMelatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. … The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesSynonyms: N-[2-(5-methoxyindol-3-yl)ethyl]acetamide, 5-methoxy-N-acetyl tryptamineLeucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigational[L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic … Leucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis.
Mixtures: FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADET, KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK.Categories: Vitamin B Complex, Heterocyclic Compounds, 2-RingFlucytosine
go.drugbank.com/drugs/DB01099ApprovedInvestigationalA fluorinated cytosine analog that is used as an antifungal agent.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-FC, 5-FluorocytosineIsosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigational[L11743] Isosorbide mononitrate has a longer duration of action than [nitroglycerin] due to its slow onset of absorption and metabolism. … Like other organic nitrates, isosorbide mononitrate acts as a prodrug for its active metabolite, [nitric oxide], which mediates the therapeutic action of isosorbide mononitrate.
Synonyms: IS 5-MN, IS-5-MNProducts: MONOKET LONG 25 MG DEĞİŞTİRİLMİŞ SALIMLI SERT KAPSÜL, 50 ADET, MONOKET LONG 25 MG DEĞİŞTİRİLMİŞ SALIMLI SERT KAPSÜL, 30 ADETCiticoline
go.drugbank.com/drugs/DB12153ApprovedInvestigationalWithdrawnCiticoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Cytidine 5'-diphosphocholine, Cytidine-5'-diphosphocholineMetronidazole
go.drugbank.com/drugs/DB00916ApprovedInvestigationalMetronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. … A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat a
Synonyms: 1-(β-ethylol)-2-methyl-5-nitro-3-azapyrrole, 2-methyl-3-(2-hydroxyethyl)-4-nitroimidazoleInternational brands: Tricowas BPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis. … Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.
Mixtures: ACORT 15/850 MG FILM TABLET, 30 ADET, PREKO 15/850 MG FILM TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesFurosemide
go.drugbank.com/drugs/DB00695ApprovedInvestigationalVet approved[A182495] The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. … Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative.
Mixtures: Lasitace 5 mg/40 mg Kapseln, Lasitace 5 mg/20 mg KapselnSynonyms: 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid, 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acidPentobarbital
go.drugbank.com/drugs/DB00312ApprovedVet approvedA short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersSynonyms: 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-ethyl-5-(1-methylbutyl)barbituric acidMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalDiabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. … [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD).
Mixtures: ESPAVEN MD, PCP 100 KitCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates