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Donepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigationalDonepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. … In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990.
Mixtures: GINKOREM 10/80 MG EFERVESAN TABLET, 84 ADET, DOMINGO 10/10/80 MG EFERVESAN TABLET, 30 ADETProducts: DONEPEZIL EG, ANDEM 10 MG FILM TABLET, 84 ADETTramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigationalthat both contribute to its analgesic property through different mechanisms and are also themselves metabolized into active metabolites: (+)-tramadol and its primary metabolite (+)-O-desmethyl-tramadol (M1 … Tramadol differs from other traditional opioid medications in that it doesn't just act as a μ-opioid agonist, but also affects monoamines by modulating the effects of neurotransmitters involved in the
Mixtures: ZALDIAR 37,5 MG/325 MG FİLM KAPLI TABLET, 10 ADET, ZALDIAR 37,5 MG/325 MG FİLM KAPLI TABLET, 20 ADETProducts: TRAMADOLO EG, Ultram ERLeucovorin
go.drugbank.com/drugs/DB00650ApprovedInvestigational[L56091, L56092] Historically developed in 1945, leucovorin has long been a staple on the World Health Organization’s List of Essential Medicines. … [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic
Synonyms: 10-Formyl-7,8-dihydrofolic acid, N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acidMixtures: FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADET, KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK.Pantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigationalPantoprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme … increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis and bone fractures later in life.
Products: Pantoprazol Towa Pharmaceutical Europe 20 mg magensaftresistente Tabletten, Pantoprazol Towa Pharmaceutical Europe 40 mg magensaftresistente TablettenIbutilide
go.drugbank.com/drugs/DB00308ApprovedIbutilide is a Class III antiarrhythmic agent available in intravenous formulations.
Synonyms: N-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamideProducts: Fybrio 1 mg/10 ml I.V. Enjeksiyonluk Çözelti, 1 ADET, Corvert 87 Mikrogramm/ml InfusionslösungGadoversetamide
go.drugbank.com/drugs/DB00538ApprovedGadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Categories: Compounds used in a research, industrial, or household settingProducts: CIPROFLOXACINA 100 MG / 10 ML, OPTIMARK 500 MIKROMOL/ML IV. ENJ. ICIN COZ. ICEREN FLAKON, 10 MLRanitidine
go.drugbank.com/drugs/DB00863ApprovedWithdrawn[L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. … [A176843] Ranitidine has proven to be an effective treatment for relieving uncomfortable symptoms of gastric acid associated conditions and is therefore widely used in GERD and other gastric-acid related
Products: RANITIDINA 50 MG EN SODIO CLORURO 0.7% POR 100 ML (INFUSION), RANITIDINA 50MG EN SODIO CLORURO 0.7 % POR 50 ML INFUSIONMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAn anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. … the risk of colorectal cancer in conditions like ulcerative colitis is maintained.
Synonyms: m-Aminosalicylic acidProducts: MESALAZINA EG, MESALAZINA EG STADADexketoprofen
go.drugbank.com/drugs/DB09214ApprovedInvestigationalWithdrawnIt is available in the various countries in Europe, Asia and Latin America. It has analgesic, antipyretic and anti-inflammatory properties [L1298].
International brands: FEN LIMixtures: DEKSİT 25 MG/8 MG TABLET, LEODEX PLUS 50 MG/8 MG FILM KAPLI TABLET,10 TABLETPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalIts use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907] … It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative
Products: Pemetrexed Zentiva 10 mg/ml Infusionslösung, PEMETREXED EG