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Displaying results 291 - 300 of 10000 in total
  1. Drug

    Idelalisib

    go.drugbank.com/drugs/DB09054
    ApprovedInvestigational

    By inhibiting this enzyme, idelalisib induces apoptosis of malignant cells and inhibits several cell signaling pathways, including B-cell receptor (BCR) signaling and C-X-C chemokine receptors type 5 and … Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one, 5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-one
  2. Drug

    (S)-2-((S)-3-isobutyl-2,5-dioxo-4-quinolin-3-ylmethyl-[1,4]diazepan-1yl)-N-methyl-3-naphtalen-2-yl-propionamide

    go.drugbank.com/drugs/DB04724
    Experimental

    Synonyms: (S)-2-((S)-3-isobutyl-2,5-dioxo-4-quinolin-3-ylmethyl-[1,4]diazepan-1yl)-N-methyl-3-naphtalen-2-yl-propionamide
  3. Drug

    Tiphenamil

    go.drugbank.com/drugs/DB19367
    Experimental

    Synonyms: -phenyl-, s-(2-(diethylamino)ethyl) ester, Benzeneethanethioic acid, a-phenyl-, s-(2-(diethylamino)ethyl) ester
  4. Drug

    (+)-1-bromo-2-propanol

    go.drugbank.com/drugs/DB03335
    Experimental

    Synonyms: (S)-(+)-1-Bromo-2-propanol, (+)-1-bromo-2-propanol
  5. Drug

    alpha-Methylleucine

    go.drugbank.com/drugs/DB04063
    Experimental

    Synonyms: (S)-2-Methylleucine, 2-Methyl-L-leucine
  6. Drug

    GX-19 Vaccine

    go.drugbank.com/drugs/DB15891
    Investigational

    As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488]. … The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758].

    Synonyms: DNA vaccine expressing SARS-CoV-2 S-protein antigen
  7. Drug

    (2S)-2-cyano-1-(4-phenyl-L-phenylalanyl)pyrrolidine

    go.drugbank.com/drugs/DB08024
    Experimental

    Synonyms: 1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE, (2S)-2-cyano-1-(4-phenyl-L-phenylalanyl)pyrrolidine
  8. Drug

    Buprenorphine

    go.drugbank.com/drugs/DB00921
    ApprovedIllicitInvestigationalVet approved

    [L46571] Buprenorphine is commercially available as the brand name product Suboxone which is formulated in a 4:1 fixed-dose combination product along with [naloxone], a non-selective competitive opioid … Clinically, this results in a slow onset of action and a clinical phenomenon known as the "ceiling effect" where once a certain dose is reached, buprenorphine's effects plateau.

    Mixtures: SUBOXONE 8 MG/2 MG DILALTI TABLET, 7 ADET, Suboxone 8 mg/2 mg sublingual tabletsCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  9. Drug

    (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide

    go.drugbank.com/drugs/DB07095
    Experimental

    Synonyms: (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide
  10. Drug

    (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE

    go.drugbank.com/drugs/DB07876
    Experimental

    Synonyms: (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE