Search
Corticotropin
go.drugbank.com/drugs/DB01285ApprovedInvestigationalVet approvedIt is an important player in the hypothalamic-pituitary-adrenal axis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersAAV-AIPL
go.drugbank.com/drugs/DB17857ExperimentalDeveloped by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in _AIPL1_ gene. … AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene.
Inodiftagene vixteplasmid
go.drugbank.com/drugs/DB16017InvestigationalInodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed
Synonyms: dT-A-H19Odanacatib
go.drugbank.com/drugs/DB06670InvestigationalThe drug made it to phase III trials before abandoned due to increased stroke. … Odanacatib is an inhibiter of cathepsin K which was originally developed be Merck & Co as a new treatment for osteoporosis [A19388].
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesEthchlorvynol
go.drugbank.com/drugs/DB00189ApprovedIllicitWithdrawnIt has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Amitraz
go.drugbank.com/drugs/DB11373ExperimentalVet approvedAmitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. … Its insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with the octopamine receptors in the central nervous system and its driven inhibition of the synthesis
Synonyms: 1,5-di(2,4-dimethylphenyl)-3-methyl-1,3,5-triazapenta-1,4-dieneEHC18
go.drugbank.com/drugs/DB05114ExperimentalEHC18 is an immune regulation medicine. It is a broad spectrum of specific HCV proteins.
Safflower oil
go.drugbank.com/drugs/DB09446ApprovedInvestigationalWithdrawnGamma linolenic acid (GLA) safflower oil is marketed as an over-the-counter dietary supplement. … Safflower oil with a higher content of polyunsaturated fatty acids is more commonly used as an edible oil.
Vigabatrin
go.drugbank.com/drugs/DB01080ApprovedInvestigational[A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was used extensively until 1997, when an association with vision loss became apparent. … Vigabatrin is an analog of gamma-aminobutyric acid ([GABA]), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms.
Categories: Cytochrome P-450 CYP2C9 Inducers, Cytochrome P-450 Enzyme Inducers