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Sevelamer
go.drugbank.com/drugs/DB00658ApprovedInvestigationalSevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Categories: Compounds used in a research, industrial, or household settingProducts: <html>RENALAMER CO<sub>3</sub> 800 MG FILM TABLET, 180 ADET</html>, RENADIN 800 MG FILM TABLET, 180 ADETSilodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigationalneck, prostate, and prostatic urethra: the α<sub>1A</sub> subtype accounts for approximately 75% of α1-adrenoceptors in the prostate. … Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: SİLODOPİN 4 MG KAPSÜL, 30 ADET, SİLODOPİN 8 MG KAPSÜL, 30 ADETClofazimine
go.drugbank.com/drugs/DB00845ApprovedInvestigationalWithdrawnClofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as [dapsone], for the treatment of leprosy. … It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of the skin and bodily fluids.
Categories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 CYP2C8 InhibitorsProducts: Fazim 50 mg Capsule, CLOFZIMIN® 100 MGCiclesonide
go.drugbank.com/drugs/DB01410ApprovedInvestigationalCiclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Mixtures: LUXNID 2/200 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL,120 KAPSÜL, LUXNID 2/400 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL,120 KAPSÜLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesScopolamine
go.drugbank.com/drugs/DB00747ApprovedInvestigational[A228773, L31578] Scopolamine was first approved by the FDA on December 31, 1979, and is currently available as both oral tablets and a transdermal delivery system.[L31578] … [A228758, L31578] Due to its dose-dependent adverse effects, scopolamine was the first drug to be offered commercially as a transdermal delivery system, Scopoderm TTS®, in 1981.
Mixtures: Me-PB-Hyos, Me-PB-HyosCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTafamidis
go.drugbank.com/drugs/DB11644ApprovedInvestigational[A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]
Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(3,5-Dichlorophenyl)benzoxazole-6-carboxylic acid, 6-BENZOXAZOLECARBOXYLIC ACID, 2-(3,5-DICHLOROPHENYL)-Afatinib
go.drugbank.com/drugs/DB08916ApprovedInvestigationalAfatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. … For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: GIOTRIF® 50 MG, GIOTRIF® 30 MGAgalsidase alfa
go.drugbank.com/drugs/DB15874ApprovedInvestigational[A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413] … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta].
Synonyms: alpha-D-galactosidase, alpha-galactosidase AProducts: REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/MLApis mellifera venom
go.drugbank.com/drugs/DB10955ApprovedApis mellifera venom is an extract of Apis mellifera venom. Apis mellifera venom is used in allergenic testing.
Mixtures: ALUTARD SQ Bienengift Injektionssuspension (Anfangsbehandlung) (100 SQ E/ml, 1.000 SQ E/ml, 10.000 SQ E/ml und 100.000 SQ E/ml), ALUTARD SQ Bienengift Injektionssuspension (Anfangsbehandlung) (100 SQ E/ml, 1.000 SQ E/ml, 10.000 SQ E/ml und 100.000 SQ E/ml)Products: Venomil Honey Bee Venom (120 Mcg), ALUTARD SQ Bienengift 100.000 SQ-E/ml Injektionssuspension (Fortsetzungsbehandlung)Nystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approved[A188562] Nystatin has a greater antifungal activity than amphotericin B - parenterally administered nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate … Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably _Candida_ species.
Mixtures: NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 6 ADET, NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 12 ADETCategories: Compounds used in a research, industrial, or household setting