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Piclidenoson
go.drugbank.com/drugs/DB05511InvestigationalIts novel mechanism of action relies on antagonism of adenoside A3 receptors. CF101 is supplied as an oral drug and has an excellent safety profile.
Sitimagene ceradenovec
go.drugbank.com/drugs/DB04907ExperimentalIt is being developed by Ark Therapeutics. … Sitimagene ceradenovec is a novel gene-based product for the treatment of patients with operable high grade glioma, a type of malignant brain tumour, given in addition to standard surgery and radiotherapy
AC-100
go.drugbank.com/drugs/DB05671InvestigationalIt is being developed by Acologix, Inc. … AC-100 is a novel synthetic peptide derived from an endogenous human protein produced by bone and dental cells (a fragment from matrix extracellular phosphoglycoprotein).
Edrophonium
go.drugbank.com/drugs/DB01010ApprovedIt has also been used as an antidote to curare principles.
Synonyms: 3-hydroxy-N,N-dimethyl-N-ethylanilinium, N-ethyl-3-hydroxy-N,N-dimethylaniliniumCiclopirox
go.drugbank.com/drugs/DB01188ApprovedInvestigationalCiclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective ...
Erdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationalErdosteine has been shown to be safe and well tolerated in clinical trials. … Co-administration of erdosteine and amoxicillin in patients with acute infective exacerbation of chronic bronchitis resulted in higher concentrations of the antibiotic in the sputum, leading to earlier
Ranpirnase
go.drugbank.com/drugs/DB04950InvestigationalIt is manufactured by Alfacell Corporation. It is the first ribonuclease to enter cancer clinical trials.
Tedisamil
go.drugbank.com/drugs/DB06200ExperimentalIt is currently being developed by Solvay and is currently under regulatory review by the United States Food and Drug Administration.
Zomepirac
go.drugbank.com/drugs/DB04828ApprovedWithdrawnZomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.
Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSDegarelix
go.drugbank.com/drugs/DB06699ApprovedInvestigationalFDA approved on December 24, 2008. … Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH.