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Displaying results 3131 - 3140 of 7284 in total
  1. Drug

    Talorasib

    go.drugbank.com/drugs/DB21686
    Experimental

    Talorasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Talorasib is a Ras protein inhibitor. Talorasib has a monoisotopic molecular weight of 604.24 Da.

  2. Drug

    Girocitinib

    go.drugbank.com/drugs/DB21692
    Experimental

    Girocitinib has a monoisotopic molecular weight of 326.14 Da. … Girocitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Girocitinib is a Janus kinase inhibitor.

  3. Drug

    Nedemelteon

    go.drugbank.com/drugs/DB21700
    Experimental

    Nedemelteon has a monoisotopic molecular weight of 258.14 Da. … Nedemelteon is a small molecule drug. The usage of the INN stem '-melteon' in the name indicates that Nedemelteon is a melatonin receptor agonist.

  4. Drug

    Dostarlimab

    go.drugbank.com/drugs/DB15627
    ApprovedInvestigational

    A prospective phase II study in patients with mismatch repair-deficient locally advanced rectal cancer resulted in all twelve patients exhibiting a complete clinical response.[A248905] … [L33340] A companion diagnostic device - the VENTANA MMR RxDx Panel - was also approved alongside this indication to select appropriate patients for treatment.

  5. Drug

    Icodextrin

    go.drugbank.com/drugs/DB00702
    ApprovedInvestigational

    It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways.

    Mixtures: SOLUCIÓN DP PISA DXTCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Estradiol benzoate

    go.drugbank.com/drugs/DB13953
    ApprovedVet approvedWithdrawn

    Estradiol Benzoate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human body. … First-pass metabolism by the gut and the liver quickly degrades the estradiol molecule before it gets a chance to enter systemic circulation and exert its estrogenic effects [A12102].

    Synonyms: benzoato de estradiol
  7. Drug

    Dalfampridine

    go.drugbank.com/drugs/DB06637
    ApprovedInvestigational

    FDA approved on January 22, 2010. … Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients.

    Categories: OCT2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index
  8. Drug

    Inodiftagene vixteplasmid

    go.drugbank.com/drugs/DB16017
    Investigational

    Inodiftagene vixteplasmid is a plasmid DNA vector encoding the diphtheria toxin A (dT-a) gene under transcriptional regulation of the promoter region of the human H19 gene (an imprinted maternally expressed

    Synonyms: dT-A-H19, diphtheria-toxin-A-H19
  9. Drug

    Detirelix

    go.drugbank.com/drugs/DB19488
    Experimental

    Detirelix has a monoisotopic molecular weight of 1536.78 Da. … Detirelix is a small molecule drug. The usage of the INN stem '-relix' in the name indicates that Detirelix is a gonadotropin-releasing-hormone (GnRH) inhibitor.

  10. Drug

    Xantocillin

    go.drugbank.com/drugs/DB19495
    Experimental

    Xantocillin has a monoisotopic molecular weight of 288.09 Da. … Xantocillin is a small molecule drug. The usage of the INN stem '-cillin' in the name indicates that Xantocillin is a antibiotic, 6-aminopenicillanic acid derivative.