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Displaying results 3181 - 3190 of 10000 in total
  1. Drug

    Ceftolozane

    go.drugbank.com/drugs/DB09050
    ApprovedInvestigational

    Ceftolozane is a semi-synthetic broad-spectrum fifth generation cephalosporin. … [L6685] It was approved by the FDA in 2014 for use in combination with [Tazobactam] for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections.

    Synonyms: 4.2.0]oct-2-ene-2-carboxylate, (6R,7R)-3-([3-Amino-4-(2-aminoethylcarbamoylamino)-2-methylpyrazol-1-ium-1-yl]methyl)-7-([(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino)-8-oxo-5-thia-1-azabicyclo[Mixtures: ZERBAXA ® 1 G/0.5 G, ZERBAXA ® 1 G/0.5 G
  2. Drug

    Cinalukast

    go.drugbank.com/drugs/DB00587
    Experimental

    Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. … Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.

    Synonyms: 3'-((E)-2-(4-cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acidCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    ORC-13661

    go.drugbank.com/drugs/DB18903
    Investigational

    ORC-13661 is under investigation in clinical trial NCT05730283 (Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin).

    Synonyms: (1R,8S)-4-{[(4-chlorophenyl)carbamoyl]amino}-11-methyl-5-thia-11-azatricyclo[6.2.1.0<sup>2,6</sup>]undeca-2-(6),3-diene-3-carboxamide, (4R,6S)-2-[[[(4-Chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro-5-methyl-4,6-ethanothieno[3,2-c]pyridine-3-carboxamideCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    N-[(2S,3S)-4-[2-[(5S)-3a,4,5,6,7,7a-Hexahydro-1,3-benzodioxol-5-yl]ethyl-[3-(1,3-dioxoisoindol-2-yl)propanoyl]amino]-3-hydroxy-1-phenylbutan-2-yl]-3,5-dimethoxy-4-phenylmethoxybenzamide

    go.drugbank.com/drugs/DB03063
    Experimental

    Synonyms: N-[(2S,3S)-4-[2-[(5S)-3a,4,5,6,7,7a-Hexahydro-1,3-benzodioxol-5-yl]ethyl-[3-(1,3-dioxoisoindol-2-yl)propanoyl]amino]-3-hydroxy-1-phenylbutan-2-yl]-3,5-dimethoxy-4-phenylmethoxybenzamide
  5. Drug

    Supinoxin

    go.drugbank.com/drugs/DB19010
    Investigational

    Supinoxin is under investigation in clinical trial NCT02003092 (RX-5902 Treatment of Subjects With Triple Negative Breast Cancer).

    Synonyms: 1-piperazinecarboxamide, 4-(3,5-dimethoxyphenyl)-n-(7-fluoro-3-methoxy-2-quinoxalinyl)-, 4-(3,5-dimethoxyphenyl)-n-(7-fluoro-3-methoxy-quinoxalin-2-yl)piperazine-1-carboxamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    Imifoplatin

    go.drugbank.com/drugs/DB17120
    Investigational

    Synonyms: Dihydrogen (sp-4-2)-((1r,2r)-cyclohexane-1,2-diamine-.kappa.2n1,n2)(diphosphato(4)-.kappa.2o1,o3)platinate(2), Platinate(2-), ((1r,2r)-1,2-cyclohexanediamine-.kappa.n1,.kappa.n2)(diphosphato(4-)-.kappa.o,.kappa.o'')-, hydrogen (1:2), (sp-4-2)-
  7. Drug

    Vodobatinib

    go.drugbank.com/drugs/DB17141
    Investigational

    Synonyms: 2-chloro-6-methyl-n'-(4-methyl-3-(2-(quinolin-3-yl)ethynyl)benzoyl)benzohydrazide, 4-methyl-3-quinolin-3-yl-ethynyl benzoic acid n'-(2-chloro-6-methylbenzoyl)hydrazide
  8. Drug

    Lanimostim

    go.drugbank.com/drugs/DB06559
    Experimental

    Synonyms: 4-221-Colony-stimulating factor 1 (human clone p3ACSF-69 reduced)
  9. Drug

    Cephaloglycin

    go.drugbank.com/drugs/DB00689
    Approved

    A cephalorsporin antibiotic that is no longer commonly used.

    Synonyms: 7-(D-2-Amino-2-phenylacetamido)-3-acetoxymethyl-delta(sup3)-cephem-4-carboxylic acid, 7-(2-D-alpha-Aminophenylacetamido)cephalosporanic acidCategories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Iltamiocel

    go.drugbank.com/drugs/DB19059
    Investigational

    Synonyms: COOK MYOSITES AUTOLOGOUS MUSCLE DERIVED CELLS (AMDC) ARE EXPANDED (AMPLIFIED) THROUGH A TWO-PHASE MANUFACTURING PROCESS.