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GALE-301
go.drugbank.com/drugs/DB17262InvestigationalIt is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune adjuvant, granulocyte macrophage-colony stimulating factor (GM-CSF).[A254696,L44166,L44171]
RPI-MN
go.drugbank.com/drugs/DB17957ExperimentalRPI-MN is a detoxified or chemically modified alpha-cobratoxin with antiviral properties. … [A260132] Being developed by Nutra Pharma under the trade name PEPTERON, it is being investigated for the treatment of neurological and immune disorders.[L47107]
Synonyms: RPI-MNBaxdrostat
go.drugbank.com/drugs/DB19090ApprovedInvestigationalIt targets aldosterone excess, a primary underlying driver of treatment resistance and organ damage in cardiovascular diseases [A275512, A275515].
Ethylhexyl methoxycrylene
go.drugbank.com/drugs/DB11226ApprovedIt currently enjoys regional approvals in Canada, the EU, and the US [L2847]. … It returns UV filters to their ground states without absorbing sunlight [F104].
Formestane
go.drugbank.com/drugs/DB08905ApprovedWithdrawnFormestane has poor oral bioavailability, and thus must be administered fortnightly (bi-weekly) by intramuscular injection. … It is listed as a prohibited substance by the World Anti-Doping Agency for use in athletes.
Stearic acid
go.drugbank.com/drugs/DB03193ApprovedIt is a waxy solid.
Mixtures: Huile D'onagre Vitamin E, O Hui Veil Fit Dual Foundation 20Products: G Pore Deep Clearing FoamBerotralstat
go.drugbank.com/drugs/DB15982ApprovedInvestigational[A225106] Berotralstat was first approved by the FDA on December 3, 2020, as the first once-daily oral therapy to prevent angioedema attacks of HAE in adults and pediatric patients 12 years and older. … [L26661] It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE.
Droxidopa
go.drugbank.com/drugs/DB06262ApprovedInvestigationalProvided L-DOPS successfully completes clinical trials, it could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. … Though L-DOPS has been used in Japan and Southeast Asia already for some time, it is also currently in clinical trials at the phase III point in the United States (U.S.), Canada, Australia, and throughout
Synonyms: L-DOPS, L-DihydroxyphenylserineOsilodrostat
go.drugbank.com/drugs/DB11837ApprovedInvestigational[A191850] Osilodrostat was approved for use in the EU in January 2020 for the treatment of endogenous Cushing's syndrome (i.e. … Cushing's disease),[A191850] and was granted FDA approval and Orphan Drug designation in the US in March 2020 for the same indication.[L12162]
Benzethonium
go.drugbank.com/drugs/DB11125ApprovedIt is shown to be effective in mediating its antimicrobial action against bacteria, fungi, mold and viruses. … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments.
Mixtures: Sanitary Wet Wipes, Disinfectant Wet WipesProducts: Hand-E-foam, Hand-Giene E-2