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LCL-161
go.drugbank.com/drugs/DB12085InvestigationalLCL161 has been used in trials studying the treatment of Leukemia, Neoplasms, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.
Synonyms: (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamideCategories: Heterocyclic Compounds, 1-Ring, Proto-Oncogene Proteins c-bcl-2, antagonists & inhibitorsMetamfetamine
go.drugbank.com/drugs/DB01577ApprovedIllicitInvestigationalWithdrawnIt is a scheduled drug in most countries due to its high potential for addiction and abuse. … Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine group of sympathomimetic amines.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 SubstratesSynonyms: d-1-phenyl-2-methylaminopropane, d-N-methylamphetamineCitarinostat
go.drugbank.com/drugs/DB15449InvestigationalCitarinostat is under investigation in clinical trial NCT02886065 (A Study of PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM).
Synonyms: (2-((2-chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide)Categories: Heterocyclic Compounds, 1-RingPalazestrant
go.drugbank.com/drugs/DB18971InvestigationalPalazestrant is under investigation in clinical trial NCT06016738 (OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer).
Synonyms: (1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1-{4-[(1-propylazetidin-3- yl)oxy]phenyl}-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole, 1H-Pyrido[3,4-b]indole, 2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-1-[4-[(1-propyl-3-azetidinyl)oxy]phenyl]-, (1R,3R)-Zinlirvimab
go.drugbank.com/drugs/DB18867InvestigationalZinlirvimab is under investigation in clinical trial NCT03707977 (Dual Bnab Treatment in Children).
Synonyms: Anti-hiv-1 human monoclonal antibody targeting v3 glycan supersite on the hiv-1 envelope protein (10-1074)Diglyme
go.drugbank.com/drugs/DB02935ExperimentalSynonyms: di(2-methoxyethyl) ether, 2,2'-oxybis(1-methoxyethane)Atisnolerbart
go.drugbank.com/drugs/DB19418InvestigationalAtisnolerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen
Synonyms: immunoglobulin G4-kappa, anti-[Bet v 1 (Betula alleghaniensis (yellow birch) pollen allergen 1], gamma4 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV1-8*03 (86.7%) -(IGHD) - IGHJ4*01 (93.3%), CDR-IMGT [8.8.13] (26-33.51- 58.97-109)) (1-120)-Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH24-nitrophenyl-beta-D-galactoside
go.drugbank.com/drugs/DB02632ExperimentalSynonyms: 1-O-(4-nitrophenyl)-β-D-galactose, 1-O-(p-nitrophenyl)-β-D-galactoseCategories: Compounds used in a research, industrial, or household settingWillardiine
go.drugbank.com/drugs/DB04129ExperimentalWillardiine is a compound isolated from seeds of _Acacia willariana_.
Categories: Heterocyclic Compounds, 1-RingSynonyms: L-WILLARDIINE, (2S)-2-AMINO-3-(2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-1-YL)PROPANOIC ACIDBersacapavir
go.drugbank.com/drugs/DB19035InvestigationalBersacapavir is under investigation in clinical trial NCT03365947 (Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)).
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 SubstratesSynonyms: 1h-pyrrole-2-carboxamide, n-(3-cyano-4-fluorophenyl)-1-methyl-4-((((1s)-2,2,2-trifluoro-1-methylethyl)amino)sulfonyl)-, N-(3-cyano-4-fluorophenyl)-1-methyl-4-(((2s)-1,1,1-trifluoro-2-propanyl)sulfamoyl)-1hpyrrole-2-carboxamide