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Displaying results 321 - 330 of 10000 in total
  1. Drug

    Lactaldehyde

    go.drugbank.com/drugs/DB03776
    Experimental

    Synonyms: (S)-lactaldehyde, (2s)-2-Hydroxypropanal
  2. Drug

    Voriconazole

    go.drugbank.com/drugs/DB00582
    ApprovedInvestigational

    Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. … [L15571] It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
  3. Drug

    Valsartan

    go.drugbank.com/drugs/DB00177
    ApprovedInvestigational

    [A174124,A173869] Valsartan was initially approved in 1996 in Europe for the treatment of hypertension in adults. Shortly after, in 1997, this drug was approved in the United States. … angiotensin I to angiotensin II through inhibition of the ACE enzyme.

    Mixtures: AMLODIPINA E VALSARTAN DOC, AMLODIPINA E VALSARTAN DOCCategories: Agents Acting on the Renin-Angiotensin System, Angiotensin 2 Receptor Blocker
  4. Drug

    (S)-2-[4-(Aminomethyl)-1h-1,2,3-Triazol-1-Yl]-4-Methylpentanoic Acid

    go.drugbank.com/drugs/DB03244
    Experimental

    Synonyms: (S)-2-[4-(Aminomethyl)-1h-1,2,3-Triazol-1-Yl]-4-Methylpentanoic Acid
  5. Drug

    Carglumic acid

    go.drugbank.com/drugs/DB06775
    ApprovedInvestigational

    Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. … Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010.

    Categories: Carbamoyl Phosphate Synthetase 1 Activator, Carbamoyl Phosphate Synthetase 1 ActivatorsSynonyms: (S)-2-ureidopentanedioic acid, N-Carbamyl-L-glutamate
  6. Drug

    Temozolomide

    go.drugbank.com/drugs/DB00853
    ApprovedInvestigational

    It is currently marketed under the trademark TEMODAR® by Merck.[L32033] … [A229853, A229923] Temozomolide as an adjunct to radiotherapy followed by maintenance dosing remains the standard of care for both Glioblastoma and refractory anaplastic astrocytoma.

    Synonyms: (S)-perillyl alcohol temozolomide, 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamideCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substrates
  7. Drug

    Methyldopa

    go.drugbank.com/drugs/DB00968
    ApprovedInvestigational

    Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading to the inhibition of adrenergic neuronal outflow and reduction of vasoconstrictor adrenergic signals. … [A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form.

    Synonyms: (S)-(-)-alpha-Methyldopa, α-methyl-L-dopaCategories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic Agonist
  8. Drug

    (S)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide

    go.drugbank.com/drugs/DB03950
    Experimental

    Synonyms: (S)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide
  9. Drug

    Phenylalanylamide

    go.drugbank.com/drugs/DB04029
    Experimental

    Synonyms: (S)-2-amino-3-phenylpropanamide, L-phenylalanine amide
  10. Drug

    Eszopiclone

    go.drugbank.com/drugs/DB00402
    ApprovedInvestigational

    It is the active stereoisomer of zopiclone, belonging to the class of drugs known as _cyclopyrrolones_. … Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (S)-Zopiclone, (S)-6-(5-Chloro-2-pyridinyl)- 7-oxo- 6,7-dihydro- 5H-pyrrolo[3,4-b]pyrazin-5-yl- 4-methyl- 1-piperazinecarboxylate