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GSK-2018682
go.drugbank.com/drugs/DB11987InvestigationalGSK2018682 has been investigated for the treatment of Multiple Sclerosis, Relapsing-Remitting.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPF-03463275
go.drugbank.com/drugs/DB11993InvestigationalPF-03463275 has been used in trials studying the treatment of Schizophrenia and Cognitive Impairments Associated With Schizophrenia.
Categories: Heterocyclic Compounds, 1-RingInterleukin-7
go.drugbank.com/drugs/DB11997InvestigationalInterleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.
Synonyms: SH-polypeptide-42, IL-7Sorivudine
go.drugbank.com/drugs/DB11998InvestigationalSorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
Categories: Heterocyclic Compounds, 1-RingPrexasertib
go.drugbank.com/drugs/DB12008InvestigationalPrexasertib has been used in trials studying the treatment and basic science of mCRPC, Leukemia, Neoplasm, breast cancer, and Ovarian Cancer, among others.
Categories: Heterocyclic Compounds, 1-RingPonesimod
go.drugbank.com/drugs/DB12016ApprovedInvestigational[A232079] Fingolimod's activity at sphingosine 1-phosphate receptor 3 was suspected to be responsible for a portion of it's adverse effects, and so more selective modulators were developed. … Ponesimod is a selective sphingosine 1-phosphate receptor 1 modulator indicated in the treatment of relapsing forms of multiple sclerosis in adults.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBenralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigational[A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction. … Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils
Categories: Interleukin-5 Receptor alpha-directed Cytolytic Antibody, Interleukin 5 Receptor alpha-directed Antibody InteractionsProducts: FASENRA®Ammonio methacrylate copolymer type A
go.drugbank.com/drugs/DB12031InvestigationalAmmonio methacrylate copolymer type a has been used in trials studying the treatment of GERD.
Synonyms: Ammonio methacrylate copolymer type AInternational brands: Eudragit RL 30 DVedroprevir
go.drugbank.com/drugs/DB12037InvestigationalVedroprevir has been investigated for the treatment of Hepatitis C, Chronic.
Categories: Heterocyclic Compounds, 2-RingEpicatechin
go.drugbank.com/drugs/DB12039InvestigationalEpicatechin has been used in trials studying the treatment of Pre-diabetes.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring