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Displaying results 3351 - 3360 of 10000 in total
  1. Drug

    Elosulfase alfa

    go.drugbank.com/drugs/DB09051
    ApprovedInvestigational

    Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. … The recommended dose is 2 mg per kg given intravenously over a minimum range of 3.5 to 4.5 hours, based on infusion volume, once every week.

    Synonyms: Recombinant human N-acetylgalactosamine-6-sulfatase, Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS)
  2. Drug

    Levosimendan

    go.drugbank.com/drugs/DB00922
    ApprovedInvestigationalWithdrawn

    Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Trimetazidine

    go.drugbank.com/drugs/DB09069
    ApprovedInvestigational

    [L33015] Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s. … Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies.

  4. Drug

    Rozanolixizumab

    go.drugbank.com/drugs/DB14919
    ApprovedInvestigational

    Rozonolixizumab itself is an IgG4P, an inactive isotype, to reduce the likelihood of unwanted chain exchange. … [A260192] As a result, the main clinical manifestation of myasthenia gravis is easily fatigable or persistent muscle weakness.

  5. Drug

    Chlorophetanol

    go.drugbank.com/drugs/DB11368
    Experimental

    Chlorophetanol is an agent known to have antifungal activities.

  6. Drug

    Ferric oxyhydroxide

    go.drugbank.com/drugs/DB14695
    Experimental

    An antiferromagnetic material; constitutes the core of natural ferritin.

  7. Drug

    IK-930

    go.drugbank.com/drugs/DB18149
    Investigational

    IK-930 is an oral, paralog-selective TEAD inhibitor.

  8. Drug

    Naltalimide

    go.drugbank.com/drugs/DB21082
    Experimental

    Naltalimide is a small molecule drug. Naltalimide has a monoisotopic molecular weight of 472.2 Da.

  9. Drug

    Fadaltran

    go.drugbank.com/drugs/DB21100
    Experimental

    Fadaltran is a small molecule drug. Fadaltran has a monoisotopic molecular weight of 419.23 Da.

  10. Drug

    Romurtide

    go.drugbank.com/drugs/DB21196
    Experimental

    Romurtide is a small molecule drug. Romurtide has a monoisotopic molecular weight of 886.56 Da.