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Chlormerodrin
go.drugbank.com/drugs/DB00534ApprovedWithdrawnThe radiolabeled form has been used as a diagnostic and research tool. It is no longer used and has been replaced with new classes of diuretic drugs.
Finafloxacin
go.drugbank.com/drugs/DB09047ApprovedWithdrawnFinafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014. … Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus.
Nafarelin
go.drugbank.com/drugs/DB00666ApprovedInvestigationalNafarelin has been used in the treatments of central precocious puberty and endometriosis.
Enlicitide
go.drugbank.com/drugs/DB22580ApprovedInvestigational[L63795] Adverse reaction frequencies were similar to placebo and the drug carries no contraindications. … PCSK9 binds low-density lipoprotein receptors (LDLR) on the surface of hepatocytes and promotes their degradation within the liver; by blocking this interaction, enlicitide increases the number of LDLRs
Fosaprepitant
go.drugbank.com/drugs/DB06717ApprovedInvestigationalIt aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Ethoheptazine
go.drugbank.com/drugs/DB08988ApprovedWithdrawnEthoheptazine is marketed under the name Zactane. It is a phenazepine based opioid analgesic. It was invented in the 1950s and is related to other drugs such as proheptazine. … Ethoheptazine is no longer marketed in the United States.
Alphacetylmethadol
go.drugbank.com/drugs/DB01555ExperimentalIllicitIt is used mainly in the treatment of narcotic dependence. [PubChem]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSaxagliptin
go.drugbank.com/drugs/DB06335ApprovedInvestigationalSaxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Nesiritide
go.drugbank.com/drugs/DB04899ApprovedInvestigationalWithdrawnNesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing).
Obecabtagene autoleucel
go.drugbank.com/drugs/DB17362ApprovedInvestigational[A265050] On November 8, 2024, obecabtagene autoleucel was approved by the FDA for the treatment of relapsed or refractory B-cell precursor acute lymphoblastic leukemia. … Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19.
Categories: Genetically-modified Autologous T Cells, CD19-Directed Genetically Modified Autologous T-cell ImmunotherapiesSynonyms: SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION., PACKAGING SIGNAL (.PSI.), THE REV RESPONSIVE ELEMENT (RRE) AND THE CENTRAL POLYPURINE TRACT (CPPT) ARE RETAIN