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Displaying results 3451 - 3460 of 10000 in total
  1. Drug

    Ramelteon

    go.drugbank.com/drugs/DB00980
    ApprovedInvestigational

    Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: RAMELDA 8 MG FILM KAPLI TABLET,30 ADET, ROZEREST 8 MG FİLM KAPLI TABLET, 10 ADET
  2. Drug

    Enzalutamide

    go.drugbank.com/drugs/DB08899
    ApprovedInvestigational

    [A252667,A252642] Due to a favorable pharmacological profile, a phase 1 study of enzalutamide was initiated in July 2007. … [L40639, A252667] Although androgen deprivation therapy (ADT) is the first-line treatment of prostate cancer and remission can be achieved, arising resistance is inevitable, becoming castration-resistant

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: XTANDI ® 40 MG, XTANDI® 40 MG
  3. Drug

    Adefovir dipivoxil

    go.drugbank.com/drugs/DB00718
    Approved

    of hepatitis B. … It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.

    International brands: A Di Xian, A Gan DingCategories: Heterocyclic Compounds, 2-Ring, Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor
  4. Drug

    TALL-104

    go.drugbank.com/drugs/DB17360
    Investigational

    Synonyms: Human major histocompatibility complex (MHC) non-restricted T-cell line 104
  5. Drug

    DCP-001

    go.drugbank.com/drugs/DB17423
    Investigational

    Synonyms: Proliferation arrested myelomonocytic leukemic cell line-derived cells with a mature dendritic cell phenotype
  6. Drug

    Finerenone

    go.drugbank.com/drugs/DB16165
    ApprovedInvestigational

    [A236544,L34739] Finerenone was granted FDA approval on 9 July 2021,[L34739] followed by the EMA approval on 11 March 2022.[L41449] … Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesProducts: KERENDİA 10 MG FİLM KAPLI TABLET, 98 ADET, KERENDİA 20 MG FİLM KAPLI TABLET, 98 ADET
  7. Drug

    Valproate bismuth

    go.drugbank.com/drugs/DB13910
    Approved

    Valproate bismuth is available in Canada in the over-the-counter medication Neo-Laryngobis.

    Products: Neo Laryngobis Enf
  8. Drug

    Prazepam

    go.drugbank.com/drugs/DB01588
    ApprovedIllicit

    Prazepam is a benzodiazepine that is used in the treatment of anxiety disorders. It is a schedule IV drug in the U.S.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: PRAZEPAM EG
  9. Drug

    Chlorphenoxamine

    go.drugbank.com/drugs/DB09007
    ApprovedWithdrawn

    It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.

    Synonyms: ETHENAMINE, 2-(1-(4-CHLOROPHENYL)-1-PHENYLETHOXY)-N,N-DIMETHYL-, 2-((P-CHLORO-.ALPHA.-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-N,N-DIMETHYLETHYLAMINEMixtures: SISTRAL C DRAJE , 20 ADET
  10. Drug

    Olaparib

    go.drugbank.com/drugs/DB09074
    ApprovedInvestigational

    [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell … [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health Canada in April 2016.[L42820]

    Synonyms: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-oneCategories: MATE 2-K Inhibitors, P-glycoprotein substrates with a Narrow Therapeutic Index