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Loncastuximab tesirine
go.drugbank.com/drugs/DB16222ApprovedInvestigationalRelapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. … [L45206] This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A protease cleavable valine-alanine linkerPixofisiran
go.drugbank.com/drugs/DB17294ExperimentalSynonyms: Rna, (a-g-a-a-g-u-u-g-g-c-a-u-g-g-u-a-g-c-c-c-u-u-g-g-g), complex with rna (c-c-c-a-a-g-g-g-c-u-a-c-c-a-u-g-c-c-a-a-c-u-u-c-u) (1:1), Cotsiranib tgf-.beta.1 si-rna free acid componentPepstatin
go.drugbank.com/drugs/DB21282ExperimentalPepstatin is a small molecule drug. Pepstatin has a monoisotopic molecular weight of 685.46 Da.
Synonyms: Pepstatin aZorevunersen
go.drugbank.com/drugs/DB16912InvestigationalSynonyms: Rna, (p-thio)(2'-o-(2-methoxyethyl))(a-g-m5u-m5u-g-g-a-g-m5c-a-a-g-a-m5u-m5u-a-m5u-m5c)Myxothiazol
go.drugbank.com/drugs/DB04741ExperimentalSynonyms: Myxothiazol ACategories: Heterocyclic Compounds, 1-Ring, Electron Transport Complex III, antagonists & inhibitorsTN-401
go.drugbank.com/drugs/DB18140InvestigationalTN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Synonyms: A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 geneIMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE
go.drugbank.com/drugs/DB08758ExperimentalSynonyms: IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE5-Thio-a/B-D-Mannopyranosylamine
go.drugbank.com/drugs/DB03414ExperimentalSynonyms: 5-Thio-a/B-D-Mannopyranosylamine