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Displaying results 3521 - 3530 of 10000 in total
  1. Drug

    Lazertinib

    go.drugbank.com/drugs/DB16216
    ApprovedInvestigational

    [A264289] It was approved by the FDA on August 19, 2024.[L51189] Lazertinib is used alone or in combination with other chemotherapeutic agents.[L51184] … [A264299, A264304] Lazertinib was first approved in South Korea on January 18, 2021, for the treatment of _EGFR_ T790M mutation-positive non-small cell lung cancer (NSCLC) with EGFR mutations.

    Synonyms: N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE, 2-PROPENAMIDE, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)-2-PYRIMIDINYL)AMINO)-4-METHOXY-2-(4-MORPHOLINYL)PHENYL)-
  2. Drug

    Taurocholic acid

    go.drugbank.com/drugs/DB04348
    Approved

    The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagog...

    Mixtures: Herbalax Forte No 70 TabCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Morus alba pollen

    go.drugbank.com/drugs/DB10480
    Approved

    Morus alba pollen is mainly used in allergenic testing.

    Mixtures: Western 10 Tree Pollen Mix, Western 10 Tree Pollen Mix
  4. Drug

    Asparaginase Erwinia chrysanthemi

    go.drugbank.com/drugs/DB08886
    ApprovedInvestigational

    Asparaginase _Erwinia chrysanthemi_ is an asparaginase-specific enzyme derived from _Erwinia_ _chrysanthemi_ used as an anticancer agent. … It works by depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and cell survival of malignant cells, leading to cell death.

  5. Drug

    Chlormadinone

    go.drugbank.com/drugs/DB13528
    Investigational

    Mixtures: BELARA 0.03 mg/2 mg film-coated tablets, GYNORELLE 30®
  6. Drug

    Dendryphiella vinosa

    go.drugbank.com/drugs/DB11025
    Approved

    Dendryphiella vinosa extract is used in allergenic testing.

    Mixtures: Molds - Mold Mix 10, Molds - Mold Mix 10
  7. Target

    Light-harvesting protein B-800/820 beta chain

    go.drugbank.com/bio_entities/BE0003922
    TargetRhodopseudomonas acidophila

    Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.

    Synonyms: LH3 complex subunit beta
  8. Drug

    Obeticholic acid

    go.drugbank.com/drugs/DB05990
    ApprovedInvestigational

    Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected to be granted full approval for this indication in 2020.[L12636]

  9. Drug

    Rosin

    go.drugbank.com/drugs/DB11165
    Approved

    In the pharmaceuticals, rosin is used in film forming and coating tablets and enterically administered agents, as well as forming microcapsules and nanoparticles. … Rosin has shown to mediate antibacterial actions on Gram-positive bacterial species [A27267].

    Categories: Compounds used in a research, industrial, or household setting, Complex Mixtures
  10. Drug

    Trimethadione

    go.drugbank.com/drugs/DB00347
    ApprovedWithdrawn

    An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)