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PSN9301
go.drugbank.com/drugs/DB05001ExperimentalPSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indicate that it may be an ideal product candidate for meal-related dosing. … PSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the treatment of type 2 diabetes.
AT9283
go.drugbank.com/drugs/DB05169InvestigationalAT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer.
Cinnamyl alcohol
go.drugbank.com/drugs/DB14186ApprovedSensitivity to cinnamyl alcohol may be identified with a clinical patch test.
Polycarbophil
go.drugbank.com/drugs/DB09311ApprovedWithdrawnThis drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea. … Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali.
Lebrikizumab
go.drugbank.com/drugs/DB11914ApprovedInvestigational[A262874,A262879] On November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYSS for the treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12
Categories: Agents for Dermatitis, Excluding CorticosteroidsAmibegron
go.drugbank.com/drugs/DB05395InvestigationalAmibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility.
Categories: Adrenergic beta-3 Receptor AgonistsEtoperidone
go.drugbank.com/drugs/DB09194ApprovedWithdrawnEtoperidone is an atypical antidepressant introduced in Europe in 1977. … It is a phenylpiperazine-substituted triazole derivative with a composition that classifies it as an analog of tradozone and presents a similar pharmacological profile.
Categories: Serotonin Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsVotucalis
go.drugbank.com/drugs/DB05032InvestigationalrEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.
Apramycin
go.drugbank.com/drugs/DB04626InvestigationalVet approvedApramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria. … It is not approved for use in humans.
Ebastine
go.drugbank.com/drugs/DB11742ApprovedInvestigationalWithdrawnEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Categories: Antihistamines for Systemic Use, Cytochrome P-450 Substrates