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Darbepoetin alfa

Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.

Dovitinib

Chiron currently has three ongoing Phase I clinical trials for dovitinib.

Invert sugar

[A32124] Invert sugar is FDA approved since 1988 as a safe substance (GRAS).

UCB7362

It has shown high potency in biochemical (IC₅₀ = 7 nM), _in vitro_ (_P. falciparum_ 3D7 lactate dehydrogenase growth inhibition assay IC₅₀ = 10 nM), and _in vivo_ (50 mg/kg dose

Arzoxifene

Trimethobenzamide

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic respon...

Rozanolixizumab

[L47122] Rozanolixizumab was also approved by the European Commission on January 5, 2024.[L50973] … [L47122] It was granted orphan drug designation by the FDA in 2019, by the European Medicines Agency (EMA) in April 2020, and by the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) in November

Yellow fever vaccine

Symptoms of Yellow fever can range from asymptomatic, to mild flu-like illness, to more severe symptoms such as shock, jaundice, internal bleeding, and organ failure [L1655]. … The World Health Organization recommends routine vaccination in countries where Yellow Fever is endemic, and for travellers going to endemic areas as proof of vaccination is often a requirement at border

Nafarelin

Nafarelin has been used in the treatments of central precocious puberty and endometriosis.

Talorasib

The usage of the INN stem '-rasib' in the name indicates that Talorasib is a Ras protein inhibitor. Talorasib has a monoisotopic molecular weight of 604.24 Da.