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Sparteine
go.drugbank.com/drugs/DB06727ApprovedWithdrawnIt is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents. … Sparteine is a plant alkaloid derived from _Cytisus scoparius_ and _Lupinus mutabilis_ which may chelate calcium and magnesium.
Categories: Antiarrhythmics, Class Ia, Cytochrome P-450 SubstratesModakafusp alfa
go.drugbank.com/drugs/DB16399InvestigationalMultiple Myeloma (MM)). … Modakafusp alfa is under investigation in clinical trial NCT03215030 (A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-573 in Participants With Refractory
Dihydroergocristine
go.drugbank.com/drugs/DB13345Approved[L2637] It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline.
Mixtures: TOTERJİN DAMLA, 50 CCCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMB-102 CD123 CAR
go.drugbank.com/drugs/DB17366InvestigationalMB-102 are autologous T cells genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and a truncated human epidermal growth factor receptor.
SN-38
go.drugbank.com/drugs/DB05482Investigational7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsGlenvastatin
go.drugbank.com/drugs/DB21374ExperimentalGlenvastatin is a small molecule drug. The usage of the INN stem '-vastatin' in the name indicates that Glenvastatin is a antihyperlipidaemic substance, HMG COA reductase inhibitor. … Glenvastatin has a monoisotopic molecular weight of 431.19 Da.
De Novo Triacylglycerol Biosynthesis TG(15:0/15:0/15:0)
smpdb.ca/view/SMP0016949MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...
Cardiolipin Biosynthesis CL(15:0/15:0/15:0/16:0)
smpdb.ca/view/SMP0204338MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(15:0/15:0/15:0/17:0)
smpdb.ca/view/SMP0204339MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(15:0/15:0/15:0/18:0)
smpdb.ca/view/SMP0204340MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...