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Edoxaban
go.drugbank.com/drugs/DB09075ApprovedInvestigationalbe on lifelong therapy. … In addition to once daily dosing, the benefits over warfarin also include significant reductions in hemorrhagic stroke and GI bleeding, and improved compliance, which is beneficial as many patients will
Vidarabine
go.drugbank.com/drugs/DB00194ApprovedWithdrawnIt has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the
ATN-161
go.drugbank.com/drugs/DB05491InvestigationalIt inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis. … This approach targeting both the tumor vasculature and the cancer cells themselves, may be effective in single therapy as well as combination therapy.
Fluocinonide
go.drugbank.com/drugs/DB01047ApprovedInvestigationalA topical glucocorticoid used in the treatment of eczema.
Products: Lidex-EUrethane
go.drugbank.com/drugs/DB04827ApprovedWithdrawnUrethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963.
Levmetamfetamine
go.drugbank.com/drugs/DB09571ApprovedLevomethamphetamine, the L-enantiomer of methamphetamine is a sympathomimetic vasoconstrictor used in some over-the-counter (OTC) nasal decongestant inhalers in the United States.
Pheniprazine
go.drugbank.com/drugs/DB09250ApprovedWithdrawnPheniprazine is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant in the 1960s. … In addition, it was used for the treatment of other conditions, such as angina pectoris and schizophrenia.
Levomethadone
go.drugbank.com/drugs/DB13515InvestigationalCategories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersRI 624
go.drugbank.com/drugs/DB05892ExperimentalRI 624 is being developed by Rinat and is currently in Phase I clinical trials.
Lonidamine
go.drugbank.com/drugs/DB06266InvestigationalIn such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs. … Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).