Search

Displaying results 3791 - 3800 of 10000 in total
  1. Drug

    Pegfilgrastim

    go.drugbank.com/drugs/DB00019
    ApprovedInvestigational

    Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, [filgrastim]. … [A187631] Due to the relatively short circulating half-life of filgrastim, a 20 kDa PEG moiety was covalently conjugated to the N-terminus of filgrastim (at the methionine residue) to develop longer-acting

    Synonyms: PEG-G-CSF, Pegylated G-CSFCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide

    go.drugbank.com/drugs/DB07397
    Experimental

    Synonyms: (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide
  3. Drug

    Tilavonemab

    go.drugbank.com/drugs/DB17014
    Investigational

    Synonyms: Immunoglobulin g4, anti-(human tau protein) (human-mus musculus monoclonal pr-1649264 .gamma.4-chain), disulfide with human-mus musculus monoclonal pr-1649264 .kappa.-chain, dimer
  4. Drug

    MK-7288

    go.drugbank.com/drugs/DB17094
    Investigational

    Synonyms: Spiro(cyclohexane-1,5'(7'h)-furo(3,4-b)pyridine)-4-carboxamide, 2'-methoxy-n-methyl-7'-oxo-n-(2-(1-piperidinyl)ethyl)-, trans-, MK-7288 free base
  5. Drug

    Iopofosine I-124

    go.drugbank.com/drugs/DB17127
    Investigational

    Synonyms: Ethanaminium, 2-((hydroxy((18-(4-(iodo-124i)phenyl)octadecyl)oxy)phosphinyl)oxy)-n,n,n-trimethyl-, inner salt, Iopofosine I-124
  6. Drug

    1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea

    go.drugbank.com/drugs/DB07789
    Experimental

    Synonyms: 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea
  7. Drug

    Amlitelimab

    go.drugbank.com/drugs/DB18835
    Investigational

    Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years … and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).

    Synonyms: Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005-2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa.-chain, dimer
  8. Drug

    Atisnolerbart

    go.drugbank.com/drugs/DB19418
    Investigational

    Atisnolerbart is under investigation in clinical trial NCT06602739 (A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen

    Synonyms: gamma4 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV1-8*03 (86.7%) -(IGHD) - IGHJ4*01 (93.3%), CDR-IMGT [8.8.13] (26-33.51- 58.97-109)) (1-120)-Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2, immunoglobulin G4-kappa, anti-[Bet v 1 (Betula alleghaniensis (yellow birch) pollen allergen 1]
  9. Drug

    Irpagratinib

    go.drugbank.com/drugs/DB18732
    Investigational

    Irpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.

    Synonyms: 2-Propenamide, N-[(3S,4S)-3-[[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]-, N-[(3S,4S)-3-[[6-(2,6-Difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]-2-propenamide
  10. Drug

    Bendamustine

    go.drugbank.com/drugs/DB06769
    ApprovedInvestigational

    Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). … Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: PURPULZ ® 180 MG/4 ML, GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE