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Mycobacterium w. Vaccine
go.drugbank.com/drugs/DB15798InvestigationalThe Mycobacterium w (M.w) vaccine is a heat-killed suspension derived from a non-pathogenic mycobacterium: mycobacterium indicus pranii.
CIGB 2020 Vaccine
go.drugbank.com/drugs/DB15808ExperimentalCIGB 2020 is a vaccine candidate administered nasally and sublingually, working to strengthen immunity in the areas administered. … As of July, 2020, a Randomized control clinical trial (RPCEC00000306) is underway to evaluate prophylaxis potential in suspected contacts of Covid-19 patients.
BacTRL-spike
go.drugbank.com/drugs/DB15811InvestigationalAs of June, 2020, the company is pursuing a Phase 1, Randomized, Observer-Blind, Placebo-Controlled Trial (NCT04334980) to test the safety and immunogenicity of the vaccine. … BacTRL-Spike is composed of a bacterial medium with colony-forming-units of live Bifidobacterium longum engineered to deliver synthetic DNA encoding spike protein from SARS-CoV-2 contained by plasmids.
Potassium aspartate
go.drugbank.com/drugs/DB15819ApprovedWithdrawnSynonyms: L-aspartate potassiumProducts: POTASSIUM L-ASPARTATECovax-19™
go.drugbank.com/drugs/DB15846InvestigationalCovax-19™, a protein-based vaccine, was developed through partnership between APC and Vaxine. It uses an insect-cell-produced recombinant SARS-CoV-2 spike protein and Vaxine’s adjuvant, Advax-SM.
Gam-COVID-Vac
go.drugbank.com/drugs/DB15848InvestigationalThe vaccine is offered in both a frozen (Gam-COVID-Vac) and freeze-dried formulation (lyophilizate; Gam-COVID-Vac Lyo). … Preliminary results suggested that all participants developed antibodies to the SARS-CoV-2 glycoproteins with a good safety profile in both trials.
SARS-CoV-2 Sclamp
go.drugbank.com/drugs/DB15849InvestigationalThe vaccine was developed using UQ’s rapid response ‘molecular clamp’ vaccine platform that locks surface proteins in a configuration that allows more robust immune responses, in combination with a well-established … Preclinical trials showed the vaccine candidate produced high levels of neutralizing antibodies, and induced a strong T-cell response.
IMM-101
go.drugbank.com/drugs/DB15850InvestigationalIMM-101 is a heat-inactivated immune-activating mycobacterial product. … As of July 2020, researchers from the Ottawa Hospital and Queen’s University, in partnership with the Canadian Cancer Society-funded Canadian Cancer Trials Group (CCTG), are conducting a trial in over
Coronavirus-Like Particle COVID-19 Vaccine
go.drugbank.com/drugs/DB15852ExperimentalA Phase 1 clinical trial was launched in July 2020 evaluating the safety, tolerability, and immunogenicity of this vaccine candidate with or without either Cpg 1018 or AS03 (NCT04450004) in adults aged
RUTI® Vaccine
go.drugbank.com/drugs/DB15853InvestigationalMuch like the BCG vaccine, the RUTI® vaccine is also being tested as a prophylactic for SARS-CoV2. … The vaccine has demonstrated a reasonable safety profile and potent stimulation of the immune response against tuberculosis.