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Displaying results 3861 - 3870 of 10000 in total
  1. Drug

    Tesamorelin

    go.drugbank.com/drugs/DB08869
    ApprovedInvestigational

    Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection. … Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients

    Synonyms: N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet), GHRH(1-44)
  2. Drug

    ZK-93423

    go.drugbank.com/drugs/DB17063
    Experimental

    ZK-93423 is a beta-carboline with muscle relaxant activity with agonistic properties at the benzodiazepine receptor.[A253172]

    Synonyms: 9H-Pyrido[3,4-b]indole-3-carboxylicacid, 4-(methoxymethyl)-6-(phenylmethoxy)-, ethyl esterCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring
  3. Drug

    PIK-75

    go.drugbank.com/drugs/DB17047
    Experimental

    PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097]

    Synonyms: Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazideCategories: Phosphatidylinositol 3-Kinases, antagonists & inhibitors
  4. Drug

    Brilaroxazine

    go.drugbank.com/drugs/DB09226
    Investigational

    Brilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. Reviva Pharmaceuticals also intends to investigate ...

    Synonyms: 6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-oneCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor Antagonists
  5. Drug

    24,25-Dihydroxycholecalciferol

    go.drugbank.com/drugs/DB18029
    Experimental

    Synonyms: 2,3-heptanediol, 2-methyl-6-((1r,3as,4e,7ar)-octahydro-4-((2z)-2-((5s)-5-hydroxy-2-methylenecyclohexylidene)ethylidene)-7a-methyl-1h-inden-1-yl)-, (6r)-, 24,25-dihydroxyvitamin d 3Categories: Vitamin D and Analogues
  6. Drug

    N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide

    go.drugbank.com/drugs/DB08349
    Experimental

    Synonyms: N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
  7. Drug

    Birabresib

    go.drugbank.com/drugs/DB15189
    Investigational

    Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).

    Synonyms: 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thienol[3,2,-f]-[1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-hydroxyphenyl)-acetamide
  8. Drug

    Tocofersolan

    go.drugbank.com/drugs/DB11635
    Approved

    Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of [DB11251]. … D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis [L2371].

    Mixtures: Eye Health Areds 2 Formula, MVI 12 ADULTOCategories: Heterocyclic Compounds, 2-Ring, Vitamin E
  9. Drug

    N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide

    go.drugbank.com/drugs/DB07000
    Experimental

    Synonyms: N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide
  10. Drug

    AMG-208

    go.drugbank.com/drugs/DB08079
    Investigational

    AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.

    Synonyms: 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinolineCategories: Heterocyclic Compounds, 1-Ring