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Indomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalIndometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] … [A177871] The pharmacological effect of indometacin is not fully understood, however, it is thought to be mediated through potent and nonselective inhibition of the enzyme cyclooxygenase (COX), which is
Products: Nu-indo Cap 25mg, Indocid Cap 25mgLinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid was initially approved in 2000 and was the first member of the oxazolidinone antibiotic class. … [L32965] Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050
Products: ZYVOX 20MG/ML GRANULES FOR ORAL SUSPENSION, LINEZOLID PHARMACIALetermovir
go.drugbank.com/drugs/DB12070ApprovedInvestigational[L1021] It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors.[A31290] Letermovir has recieved both priority and orphan drug status from the FDA. … It is currently marketed under the brand name Prevymis.[L1021]
Products: PREVYMIS 480mg/24mL (20mg/mL) concentrate for solution for infusion, PREVYMIS CONCENTRATE FOR SOLUTION FOR INFUSION 20MG/MLPenciclovir
go.drugbank.com/drugs/DB00299ApprovedPenciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Products: Fenivir - Fieberblasencreme 10mg/g Creme, EX-LOVIR % 1 KREM 2 GDarifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalThis block reduces the urgency to urinate and so it should not be used in people with urinary retention. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Products: EMSELEX 15MG RET, EMSELEX 15MG RETARDTABLTrazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigational[T646] It was initially granted FDA approval in 1981.[L3484] … [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine
Products: PMS Trazodone HCl Tab 50mg, PMS Trazodone HCl Tab 100mgLansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigationalLansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. … [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)
Mixtures: Hp-pacProducts: AGOPTON 15MG KAPSELN, LANSOPRAZOL TEVA 15MGAzathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigational[L11214] Azathiprine was granted FDA approval on 20 March 1968.[L11214] … [A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.
Products: AZATHIOPRIN HEU 50MG NET, AZATHIOPRIN AL 25MG FTAEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalIt is currently used as an immunosuppressant to prevent rejection of organ transplants. … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor.
Products: Afinitor Tablet 10mg, EVEROLIMUS EGMeperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more...
Products: Meperidine HCl Injection 10mg/ml, Meperidine HCl Injection 25mg/ml