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GPI-1485
go.drugbank.com/drugs/DB05814InvestigationalGPI 1485 is a product candidate that belongs to a class of small molecule compounds called neuroimmunophilin ligands. … In preclinical experiments, neuroimmunophilin ligands have been shown to repair and regenerate damaged nerves without affecting normal, healthy nerves.
INM004
go.drugbank.com/drugs/DB17791InvestigationalINM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being investigated to treat Shiga-toxin producing bacterial infection relating to the prevention of hemolytic
IMM101
go.drugbank.com/drugs/DB15851ExperimentalStudies with IMM-101 showed the vaccine’s ability to stimulate cancer patients’ immune systems to help kill cancer cells. … It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma [PMID: 21930686; PMID: 30107850; PMID: 27599039].
Monoctanoin
go.drugbank.com/drugs/DB06801ExperimentalMonoctanoin is used to dissolve cholesterol gallstones.
SYN-101
go.drugbank.com/drugs/DB05958ExperimentalSYN101 is comprised of an immune cell specific antibody linked to an ALK5 inhibitor payload to selectively block TGF-b signalling in immune cells.
Amlitelimab
go.drugbank.com/drugs/DB18835Investigationaland Older With Moderate-to-severe Atopic Dermatitis (COAST 2)). … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years
EW-A-401
go.drugbank.com/drugs/DB05525InvestigationalThis specific transcription factor has been shown in animal studies to increase expression of the VEGF-A gene, and to promote the growth of new blood vessels. … EW-A-401 is a circle of genetic material (plasmid DNA) that instructs the body to produce a genetically-engineered transcription factor, a protein that regulates expression of genes.
Bacteriochlorophyll A
go.drugbank.com/drugs/DB01853ExperimentalA specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A.
MEDI-547
go.drugbank.com/drugs/DB18360InvestigationalMEDI-547 is an anti-EphA1 monoclonal antibody conjugated to mcMMAF
Dithioerythritol
go.drugbank.com/drugs/DB01692ExperimentalA compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl