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Displaying results 3941 - 3950 of 10000 in total
  1. Drug

    Triacetin

    go.drugbank.com/drugs/DB16005
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Volixibat

    go.drugbank.com/drugs/DB13914
    Investigational

    the liver have been implicated in its pathogenesis[A32119]. … Inhibiting this enzyme results in a decrease of bile acids returning to the liver, which is helpful for the treatment of NASH as abnormal cholesterol metabolism and accumulation of free cholesterol in

  3. Drug

    PPI-2458

    go.drugbank.com/drugs/DB05864
    Investigational

    In preclinical studies to date, PPI-2458 has demonstrated the potent pharmacologic activity of this class of compounds while displaying an improved pharmacokinetic and toxicity profile. … This class of compounds has been shown to prevent both abnormal cell growth and the formation of new blood vessels (known as angiogenesis), which contribute to the growth of aberrant tissues in diseases

  4. Drug

    ADH-1

    go.drugbank.com/drugs/DB05485
    Investigational

    ADH-1 may have utility in a wide variety of cancers as N-cadherin is overexpressed in a variety of tumors. … ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models.

    Synonyms: l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfide
  5. Drug

    Influenza A virus A/Washington/19/2020 (H1N1) antigen (MDCK cell derived, propiolactone inactivated)

    go.drugbank.com/drugs/DB16727
    ApprovedWithdrawn

    Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.

  6. Drug

    Neosaxitoxin

    go.drugbank.com/drugs/DB12989
    Investigational

    Neosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local Anesthetic).

    Categories: Compounds used in a research, industrial, or household setting, Complex Mixtures
  7. Drug

    Norclozapine

    go.drugbank.com/drugs/DB05766
    Investigational

    It combines an atypical antipsychotic efficacy profile with the added potential benefit of enhanced cognition, thereby addressing one of the major challenges in treating schizophrenia today. … ACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA as a novel, stand-alone therapy for schizophrenia.

    Synonyms: N-Desmethylclozapine
  8. Drug

    Dolichovespula arenaria venom protein

    go.drugbank.com/drugs/DB10957
    Approved

    Dolichovespula arenaria venom protein is an extract of Dolichovespula arenaria venom. Dolichovespula arenaria venom protein is used in allergenic testing.

  9. Drug

    Polistes exclamans venom protein

    go.drugbank.com/drugs/DB11028
    Approved

    Polistes exclamans venom protein is an extract of Polistes exclamans venom. Polistes exclamans venom protein is used in allergenic testing.

  10. Drug

    Vespula pensylvanica venom protein

    go.drugbank.com/drugs/DB11031
    Approved

    Vespula pensylvanica venom protein is an extract of Vespula pensylvanica venom. Vespula pensylvanica venom protein is used in allergenic testing.