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PRX-ASL
go.drugbank.com/drugs/DB17679ExperimentalPRX-ASL is an intracellular enzyme replacement therapy designed to replace the missing or defective enzyme in patients with argininosuccinate lyase deficiency.
Ilginatinib
go.drugbank.com/drugs/DB12784InvestigationalNS-018 has been used in trials studying the treatment of Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, and Post-Essential Thrombocythemia Myelofibrosis.
Synonyms: (S)-N-(1-(4-FLUOROPHENYL)ETHYL)-4-(1-METHYL-1H-PYRAZOL-4-YL)-N'-(PYRAZIN-2-YL)PYRIDINE-2,6-DIAMINE, 2,6-PYRIDINEDIAMINE, N2-((1S)-1-(4-FLUOROPHENYL)ETHYL)-4-(1-METHYL-1H-PYRAZOL-4-YL)-N6-2-PYRAZINYL-Rozanolixizumab
go.drugbank.com/drugs/DB14919ApprovedInvestigationalRozonolixizumab itself is an IgG4P, an inactive isotype, to reduce the likelihood of unwanted chain exchange. … [A260192] As a result, the main clinical manifestation of myasthenia gravis is easily fatigable or persistent muscle weakness.
Daledalin
go.drugbank.com/drugs/DB09189ExperimentalDaledin (UK-3557-15) is a selective norepinephrine reuptake inhibitor. It has no effects on the reuptake of serotonin or dopamine, and no antihistamine or anticholinergic properties.
Perenostobart
go.drugbank.com/drugs/DB18602InvestigationalPerenostobart is an alpha-CD39 IgG4 monoclonal antibody.
Alamifovir
go.drugbank.com/drugs/DB06368ExperimentalAlamifovir is an antiviral agent specific for HBV.
Vinylglycine
go.drugbank.com/drugs/DB03214ExperimentalVinylglycine is an irreversible inhibitor of aspartate aminotransferase.
Olokizumab
go.drugbank.com/drugs/DB13127Investigational[A241185, A241175] Olokizumab is a humanized anti-IL-6 IgG4κ antibody that directly blocks gp130 binding at IL-6 Site 3.[A241045] … Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system.