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Displaying results 31 - 40 of 91 in total
  1. Drug

    Cotoretigene toliparvovec

    go.drugbank.com/drugs/DB16797
    Investigational

    Synonyms: Adeno-associated viral vector serotype 8 containing the human RPGR gene, Adenovirus-associated viral vector serotype 8 containing the human RPGR geneCategories: Adeno-associated Viral Vector Therapies
  2. Drug

    Venlafaxine

    go.drugbank.com/drugs/DB00285
    ApprovedInvestigational

    Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood...

    Products: VENXOR 50MG TABLET, VEXTOR
  3. Drug

    Ad-RTS-hIL-12

    go.drugbank.com/drugs/DB17177
    Investigational

    Synonyms: Adenoviral vector-RheoSwitch Therapeutic System-human interleukin 12
  4. Drug

    TSHA-101

    go.drugbank.com/drugs/DB18280
    Investigational

    Synonyms: adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB
  5. Drug

    Ad5-nCoV

    go.drugbank.com/drugs/DB15655
    Investigational

    Ad5-nCoV is a recombinant adenovirus type-5 vector (Ad5) vaccine currently being investigated for prophylaxis against SARS-CoV-2.

    Synonyms: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)
  6. Drug

    AMP-101

    go.drugbank.com/drugs/DB18253
    Experimental

    AMP-101 is a gene therapy comprising an adeno-associated virus type 9 (AAV9) vector encoding the human Dok-7 protein. It is under investigation for the treatment of Dok-7-associated myasthenia.

    Synonyms: Adeno-associated virus serotype 9 vector encoding the Dok7 protein
  7. Drug

    Ofranergene obadenovec

    go.drugbank.com/drugs/DB15175
    Investigational

    Ofranergene obadenovec is under investigation in clinical trial NCT01229865 (Safety and Efficacy of VB-111 in Subjects With Advanced Differentiated Thyroid Cancer).

    Synonyms: GENETIC VECTOR CONTAINING TUMOR VASCULAR ENDOTHELIUM-DIRECTED CHIMERIC FAS ANTIGEN GENE
  8. Drug

    HUB-101

    go.drugbank.com/drugs/DB18656
    Experimental

    Synonyms: Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 gene
  9. Drug

    Avalotcagene ontaparvovec

    go.drugbank.com/drugs/DB16796
    Investigational

    Synonyms: Adeno-associated viral vector serotype 8 encoding human ornithine transcarbamylase, Recombinant adeno-associated virus serotype AAV8 vector encoding human ornithine transcarbamylaseCategories: Adeno-associated Viral Vector Therapies
  10. Drug

    Resamirigene bilparvovec

    go.drugbank.com/drugs/DB16779
    Investigational

    AT132 is under investigation in clinical trial NCT03199469 (Gene Transfer Clinical Study in X-linked Myotubular Myopathy).

    Synonyms: DNA (synthetic adeno-associated virus 8 vector AT132 human myotubularin cDNA-specifying), Non-replicating adeno-associated viral vector, serotype 8, expressing human myotubularin geneCategories: Adeno-associated Viral Vector Therapies