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Displaying results 31 - 40 of 7041 in total
  1. Drug

    RR001

    go.drugbank.com/drugs/DB17369
    Investigational

    RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand

    Synonyms: autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand
  2. Drug

    ABBV-011

    go.drugbank.com/drugs/DB18622
    Investigational

    ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.

    Synonyms: an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin
  3. Drug

    C-Alpha-stx1

    go.drugbank.com/drugs/DB17972
    Experimental

    Synonyms: Chimeric monoclonal antibody to shiga-toxin 1
  4. Drug

    Tegoprubart

    go.drugbank.com/drugs/DB16974
    Investigational

    Synonyms: Humanized Anti-Cd40Lg Igg1, Kappa Monoclonal Antibody With Heavy Chain C220S/C226S/C229S/P238S Substitutions To Attenuate Effector Function
  5. Drug

    CYNK-101

    go.drugbank.com/drugs/DB18637
    Investigational

    CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).

    Synonyms: allogeneic human placental hematopoietic stem cell derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP)
  6. Drug

    GTB-3550

    go.drugbank.com/drugs/DB18494
    Investigational

    GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of Interleukin 15 (IL-15).

    Synonyms: single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 scFV with a modified IL-15 linker
  7. Drug

    Lerodalcibep

    go.drugbank.com/drugs/DB19071
    ApprovedInvestigational

    [L54738] Approved by the FDA on December 15, 2025, lerodalcibep is indicated as an adjunct to diet and exercise to reduce low-density lipoprotein cholesterol (LDL-C) in adults with hypercholesterolemia … [A275273] Lerodalcibep prevents the actions of PCSK9 and allows more LDL to bind to LDLR and be cleared from circulation.

    Synonyms: Engineered binding protein (1-96) anti-(human proprotein convertase subtilisin/kexin type 9), derived from human tenth fibronectin type iii domain, fused via peptidyl linker (97gsgsgs102) to human serum
  8. Drug

    MK-2225

    go.drugbank.com/drugs/DB18240
    Investigational

    Synonyms: Homodimeric fragment crystallizable fusion protein comprised of the extracellular domain of the human transforming growth factor beta receptor type II linked to a human IgG1 Fc domain
  9. Drug

    Pacanalotamab

    go.drugbank.com/drugs/DB17254
    Investigational

    Synonyms: Bispecific t-cell engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and cd3
  10. Drug

    Efepoetin alfa

    go.drugbank.com/drugs/DB19197
    Investigational

    Efepoetin alfa is under investigation in clinical trial NCT04155125 (A Study of Efepoetin Alfa in Treating Anaemia Associated With Chronic Kidney Diseases Patient).

    Synonyms: Human erythropoietin (epoetin alfa) fused to a hybrid human immunoglobulin (ig), consisting of the fc fragment of the igg4 fused to the hinge and amino-terminus of the igd heavy chain isotype 2, produced